The efficacy of ginger for the prevention of postoperative nausea and vomiting: a meta-analysis
- PMID: 16389016
- DOI: 10.1016/j.ajog.2005.06.046
The efficacy of ginger for the prevention of postoperative nausea and vomiting: a meta-analysis
Abstract
Objective: The aim of this study was to specifically determine the impact of a fixed dose of ginger administration, compared with placebo, on the 24-hour postoperative nausea and vomiting.
Study design: The design was a systematic review and metaanalysis of trials revealed by searches. Randomized controlled trials comparing ginger with placebo to prevent postoperative nausea and vomiting and postoperative vomiting from Medline, IPA, CINAHL, Cochrane CENTRAL, HealthStar, Current Contents, bibliographies of retrieved articles, contact of authors, and experts in the field. Two reviewers selected studies for inclusion and independently extracted data.
Results: Five randomized trials including a total of 363 patients were pooled for analysis of preventing postoperative nausea and vomiting and postoperative vomiting. The summary relative risks of ginger for postoperative nausea and vomiting and postoperative vomiting were 0.69 (95% confidence interval 0.54 to 0.89) and 0.61 (95% confidence interval 0.45 to 0.84), respectively. Only one side effect, abdominal discomfort, was reported.
Conclusions: This meta-analysis demonstrates that a fixed dose at least 1 g of ginger is more effective than placebo for the prevention of postoperative nausea and vomiting and postoperative vomiting. Use of ginger is an effective means for reducing postoperative nausea and vomiting.
Comment in
-
Review: ginger prevents 24 hour postoperative nausea and vomiting.Evid Based Nurs. 2006 Jul;9(3):80. doi: 10.1136/ebn.9.3.80. Evid Based Nurs. 2006. PMID: 16865831 No abstract available.
Similar articles
-
Ginger (Zingiber officinale): An alternative for the prevention of postoperative nausea and vomiting. A meta-analysis.Phytomedicine. 2018 Nov 15;50:8-18. doi: 10.1016/j.phymed.2018.09.007. Epub 2018 Sep 5. Phytomedicine. 2018. PMID: 30466995
-
The preventive and relieving effects of ginger on postoperative nausea and vomiting: A systematic review and meta-analysis of randomized controlled trials.Int J Nurs Stud. 2022 Jan;125:104094. doi: 10.1016/j.ijnurstu.2021.104094. Epub 2021 Oct 1. Int J Nurs Stud. 2022. PMID: 34700257 Review.
-
Efficacy of ginger for nausea and vomiting: a systematic review of randomized clinical trials.Br J Anaesth. 2000 Mar;84(3):367-71. doi: 10.1093/oxfordjournals.bja.a013442. Br J Anaesth. 2000. PMID: 10793599 Review.
-
The effectiveness of non-invasive complementary therapies in reducing postoperative nausea and vomiting following abdominal laparoscopic surgery in women: a systematic review.JBI Libr Syst Rev. 2009;7(19):850-907. doi: 10.11124/01938924-200907190-00001. JBI Libr Syst Rev. 2009. PMID: 27819924
-
Ginger (Zingiber officinale Roscoe) preparations for prophylaxis of postoperative nausea and vomiting: A Bayesian network meta-analysis.J Ethnopharmacol. 2023 Dec 5;317:116791. doi: 10.1016/j.jep.2023.116791. Epub 2023 Jun 26. J Ethnopharmacol. 2023. PMID: 37379959
Cited by
-
Effect of Preoperative Carbohydrate Drink and Postoperative Chewing Gum on Postoperative Nausea and Vomiting in Patients Undergoing Day Care Laparoscopic Cholecystectomy: A Randomized Controlled Trial.World J Surg. 2023 Nov;47(11):2708-2717. doi: 10.1007/s00268-023-07145-8. Epub 2023 Sep 17. World J Surg. 2023. PMID: 37716930 Clinical Trial.
-
Ginger Extract and [6]-Gingerol Inhibit Contraction of Rat Entire Small Intestine.J Evid Based Integr Med. 2018 Jan-Dec;23:2515690X18774273. doi: 10.1177/2515690X18774273. J Evid Based Integr Med. 2018. PMID: 29756476 Free PMC article.
-
Chewing gum to treat postoperative nausea and emesis in female patients (CHEWY): rationale and design for a multicentre randomised trial.BMJ Open. 2019 Jun 12;9(6):e027505. doi: 10.1136/bmjopen-2018-027505. BMJ Open. 2019. PMID: 31196899 Free PMC article. Clinical Trial.
-
A randomized, double-blind, placebo-controlled trial on the efficacy of ginger in the prevention of abdominal distention in post cesarean section patients.Sci Rep. 2018 May 1;8(1):6835. doi: 10.1038/s41598-018-25200-6. Sci Rep. 2018. PMID: 29717175 Free PMC article. Clinical Trial.
-
In Vitro Antioxidant and In Vivo Lipid-Lowering Properties of Zingiber officinale Crude Aqueous Extract and Methanolic Fraction: A Follow-Up Study.Evid Based Complement Alternat Med. 2019 Jul 9;2019:9734390. doi: 10.1155/2019/9734390. eCollection 2019. Evid Based Complement Alternat Med. 2019. PMID: 31360211 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
