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Items: 5

1.

Isomaltose

A disaccharide consisting of two glucose units in an alpha (1-6) glycosidic linkage.

Year introduced: 1991(1979)

2.

Sucrase-isomaltase deficiency, congenital [Supplementary Concept]

Autosomal recessive mutations in the SI gene that cause a deficiency of sucrase-isomaltase. This disrupts the HYDROLYSIS of dietary SUCROSE and some of the products of STARCH digestion, which causes osmotic DIARRHEA when the DISACCHARIDE is ingested, because absorption cannot occur until after hydrolysis produces the component MONOSACCHARIDES. OMIM: 222900

Date introduced: August 25, 2010

3.

Oligo-1,6-Glucosidase

An enzyme that catalyzes the endohydrolysis of 1,6-alpha-glucosidic linkages in isomaltose and dextrins produced from starch and glycogen by ALPHA-AMYLASES. EC 3.2.1.10.

Year introduced: 1991(1978)

4.

sucrase-isomaltase-maltase [Supplementary Concept]

an oligo-1,4-1,6-alpha-glucosidase from Bacillus subtilis; involved in maltose and/or isomaltose metabolism; MW 66 kDa; amino acid sequence known

Date introduced: May 29, 1998

5.

glucan 1,6-alpha-isomaltosidase [Supplementary Concept]

hydrolyzes 1,6-alpha-D-glucosidic linkages in polysaccharides so as to remove successive isomaltose units from the non-reducing ends of the chains; from Arthrobacter globiformis; MW 66 kDa; amino acid sequence given in first source; GenBank D30761

Date introduced: January 20, 1995

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