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Cryopyrin-Associated Periodic Syndromes

A group of rare autosomal dominant diseases, commonly characterized by atypical URTICARIA (hives) with systemic symptoms that develop into end-organ damage. The atypical hives do not involve T-cell or autoantibody. Cryopyrin-associated periodic syndrome includes three previously distinct disorders: Familial cold autoinflammatory syndrome; Muckle-Wells Syndrome; and CINCA Syndrome, that are now considered to represent a disease continuum, all caused by NLRP3 PROTEIN mutations.

Year introduced: 2010

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Tree Number(s): C16.320.382.500, C17.800.827.368.500, C17.800.862.945.533.500.500, C17.800.862.945.766.500, C20.543.480.904.533.500.500, C20.543.480.904.766.500, C23.550.291.500.360.500.500

MeSH Unique ID: D056587

Entry Terms:

  • Cryopyrin-Associated Periodic Syndrome
  • Cryopyrin Associated Periodic Syndromes
  • Cryopyrin Associated Periodic Syndrome
  • Cryopyrinopathy
  • Cryopyrinopathies
  • Familial Cold Autoinflammatory Syndrome
  • Cold-Induced Autoinflammatory Syndrome, Familial
  • Cold Induced Autoinflammatory Syndrome, Familial
  • Cold Urticaria, Familial
  • Familial Cold-Induced Autoinflammatory Syndrome
  • Familial Cold Induced Autoinflammatory Syndrome
  • Familial Cold Urticaria
  • Familial Cold Urticarias
  • Urticaria, Familial Cold
  • Muckle-Wells Syndrome
  • Muckle Wells Syndrome
  • Syndrome, Muckle-Wells
  • Urticaria-Deafness-Amyloidosis Syndrome
  • Syndrome, Urticaria-Deafness-Amyloidosis
  • Urticaria Deafness Amyloidosis Syndrome
  • Urticaria-Deafness-Amyloidosis Syndromes
  • Urticaria, Deafness and Amyloidosis
  • UDA Syndrome
  • Syndrome, UDA
  • UDA Syndromes
  • Chronic Infantile Neurological, Cutaneous, and Articular Syndrome
  • NOMID
  • Multisystem Inflammatory Disease, Neonatal-Onset
  • Multisystem Inflammatory Disease, Neonatal Onset
  • Infantile Onset Multisystem Inflammatory Disease
  • IOMID
  • Chronic, Infantile, Neurological, Cutaneous, Articular Syndrome
  • CINCA
  • Chronic Neurologic Cutaneous and Articular Syndrome
  • Chronic Infantile Neurologic, Cutaneous, and Articular Syndrome
  • Chronic Neurologic, Cutaneous, and Articular Syndrome
  • Prieur-Griscelli Syndrome
  • Prieur Griscelli Syndrome
  • Prieur-Griscelli Syndromes
  • Syndrome, Prieur-Griscelli
  • IOMID Syndrome
  • IOMID Syndromes
  • Syndrome, IOMID
  • Neonatal Onset Multisystem Inflammatory Disease
  • CINCA Syndrome
  • Familial Cold Autoinflammatory Syndrome 1
  • FCAS1

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