Inhibitory Concentration 50

The concentration of a compound needed to reduce population growth of organisms, including eukaryotic cells, by 50% in vitro. Though often expressed to denote in vitro antibacterial activity, it is also used as a benchmark for cytotoxicity to eukaryotic cells in culture.

Year introduced: 1999

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Tree Number(s): E05.940.350, G07.690.936.563

MeSH Unique ID: D020128

Entry Terms:

• Concentration 50, Inhibitory
• IC50

Previous Indexing:

• Cell Survival/drug effects (1971-1998)

See Also:

• Microbial Sensitivity Tests

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Analytical, Diagnostic and Therapeutic Techniques and Equipment Category
Investigative Techniques
Toxicity Tests
Inhibitory Concentration 50

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Phenomena and Processes Category
Physiological Phenomena
Pharmacological and Toxicological Phenomena
Toxicological Phenomena
Inhibitory Concentration 50