Entyvio interactions: Alcohol, medications, and other factors

Entyvio interactions with other medications

Before you start treatment with Entyvio, tell your doctor and pharmacist which prescription, over-the-counter, and other medications you take. By sharing this information with them, you may help prevent possible interactions. (To learn whether Entyvio interacts with supplements, herbs, or vitamins, see the “Entyvio and other interactions” section below.)

If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.

Here’s a table of drugs that can interact with Entyvio. Keep in mind that this table doesn’t include all drugs that may interact with Entyvio. Some of these interactions are described in detail just below in “Drug interactions in depth.”

When to avoid Entyvio

In some cases, factors or conditions could prevent your doctor from prescribing Entyvio due to the risk of harm. These are known as contraindications. The contraindications of Entyvio include:

Having had an allergic reaction to Entyvio or any of its ingredients

If you’ve had an allergic reaction to Entyvio or any of its ingredients, your doctor will likely not prescribe Entyvio. Receiving the drug could cause another allergic reaction. You can ask them about other treatments that may be better choices for you.

Note: Before you start treatment with Entyvio, it’s important to tell your doctor if this contraindication applies to you. They can determine whether to prescribe Entyvio.

Entyvio interaction with alcohol

There aren’t any known interactions between Entyvio and alcohol. However, your doctor may advise you to avoid or limit alcohol consumption during Entyvio treatment.

This is because drinking alcohol while receiving the drug may worsen some of Entyvio side effects. For example, you may experience nausea or headache.

In addition, consuming large amounts of alcohol can cause liver damage. Entyvio may also cause liver damage as a side effect. This means that drinking alcohol during Entyvio treatment may increase the risk of liver problems.

Alcohol can also worsen the condition you’re receiving Entyvio to treat. For example, if you have ulcerative colitis or Crohn’s disease, drinking alcohol may worsen your symptoms.

If you consume alcohol during Entyvio treatment, these side effects may be more likely to occur. If you have questions about drinking alcohol during Entyvio treatment, talk with your doctor.

Drug interactions in depth

Here’s a closer look at certain drug interactions of Entyvio.

Natalizumab

Natalizumab (Tysabri, Tyruko) is an injection used to treat various conditions, such as multiple sclerosis (MS) and Crohn’s disease.

Interaction result: Receiving natalizumab at the same time as Entyvio can increase your risk of PML.

Interaction explained: Entyvio and natalizumab both work by weakening the immune system. With a weakened immune system, your body cannot fight off infections as well as it usually would. This can lead to a severe brain infection called PML. Using these drugs together may increase the risk of PML.

Steps you or your doctor may take: To lower the risk of PML, doctors typically won’t prescribe Entyvio if you’re receiving natalizumab. Be sure to tell your doctor if you’re receiving natalizumab before you start Entyvio. They can discuss alternative treatment options with you.

TNF inhibitors

TNF inhibitors are a class of drugs used to treat autoimmune conditions. These may include psoriatic arthritis, rheumatoid arthritis, ulcerative colitis, and Crohn’s disease.

Interaction result: Using Entyvio with a TNF inhibitor can raise your risk of infection.

Interaction explained: Similar to its interaction with natalizumab, Entyvio and TNF inhibitors both weaken the immune system. This can lead to infections or make existing infections worse. Using these medications together can increase your risk of infection.

Examples of TNF inhibitor drugs: Here are some TNF inhibitors that may interact with Entyvio:

• infliximab (Remicade)
• certolizumab (Cimzia)
• adalimumab (Humira)
• golimumab (Simponi)

Steps you or your doctor may take: Be sure to let your doctor know if you’re having treatment with a TNF inhibitor. If you do, they likely won’t prescribe Entyvio. Instead, they can discuss alternative treatment options for your condition.

Entyvio and other interactions

Entyvio may have other interactions, such as with supplements, foods, vaccines, or even lab tests. You’ll find details below. Keep in mind that the following information does not include all other possible interactions with Entyvio.

Entyvio interactions and supplements

It’s possible for drugs to interact with supplements such as vitamins and herbs.

Entyvio interactions and herbs

There are no specific reports of herbs interacting with Entyvio. However, that doesn’t mean herbal interactions won’t occur or be recognized in the future. Because of this, it’s important to check with your doctor or pharmacist before taking any of these products during Entyvio treatment.

Entyvio interactions and vitamins

There are no specific reports of vitamins interacting with Entyvio. However, that doesn’t mean vitamin interactions won’t occur or be recognized in the future. Because of this, you should talk with your doctor or pharmacist before taking any vitamin product with Entyvio.

Entyvio interactions and food

There were no reports of food interactions with Entyvio. If you’d like to learn more about eating certain foods during treatment with Entyvio, talk with your doctor.

Entyvio interactions with vaccines

Entyvio is known to interact with live vaccines. A live vaccine contains live but weakened pieces of the virus or bacterium it’s meant to defend against. When your immune system is healthy, live vaccines usually won’t cause infection.

But Entyvio works by weakening your immune system. So if you get a live vaccine, your immune system may not be able to fight the virus or bacterium. This may cause you to become sick or develop symptoms of the illness the vaccine is meant to help prevent.

Examples of live vaccines to avoid during Entyvio treatment include:

• measles, mumps, rubella (MMR)
• chickenpox
• the nasal spray form of the flu vaccine

Before starting Entyvio, talk with your doctor or pharmacist about any vaccines you may need.

Entyvio interactions and lab tests

Entyvio isn’t known to interact with any lab tests. If you have concerns about this medication interacting with lab tests, talk with your doctor.

ENTYVIO INTERACTION AND CANNABIS OR CBD

Cannabis (often called marijuana) and cannabis products, such as cannabidiol (CBD), have not been specifically reported to interact with Entyvio. However, as with any drug or supplement, talk with your doctor before using cannabis in combination with Entyvio. The effect of cannabis may affect how well you follow your Entyvio treatment plan.

Note: Cannabis is illegal at a federal level but is legal in many states to varying degrees.

Entyvio and health-related interactions

Certain medical conditions and other factors may increase the risk of interactions with Entyvio. Before you receive this drug, be sure to talk with your doctor about your health history. Entyvio may not be the right treatment option if you have certain medical conditions or other factors affecting your health.

Health conditions or factors that might interact with Entyvio include:

• Immune system disorders: Entyvio can cause PML, a rare and life threatening infection. The risk of PML may be higher if you have a condition that weakens your immune system, such as HIV or cancer. Tell your doctor if you have a condition that weakens your immune system before you start Entyvio.
• Liver problems: Entyvio can cause liver damage. If you have liver problems, the drug can worsen your condition. Be sure to let your doctor know if you have liver problems before you start Entyvio treatment. They can help determine whether Entyvio is safe for you.
• Current infection: Entyvio works by weakening your immune system. This can increase your risk of infection and make current infections worse. Due to this risk, doctors typically won’t prescribe Entyvio if you have an active infection until your infection is managed.
• Allergic reaction: If you’ve had an allergic reaction to Entyvio or any of its ingredients, your doctor will likely not prescribe Entyvio. Receiving the drug could cause another allergic reaction. You can ask them about other treatments that may be better choices for you.
• Breastfeeding: It’s not known whether it’s safe to use Entyvio while breastfeeding. Entyvio can pass into breast milk. But it’s not known if this can cause harm to a breastfed child. If you’re breastfeeding or planning to, talk with your doctor before using Entyvio. They can talk with you about treatment options and ways to feed your child.
• Pregnancy: There haven’t been enough clinical trials to determine whether Entyvio is safe to use while pregnant. If you’re pregnant or planning to become pregnant, tell your doctor before starting Entyvio. They can advise on the right treatment plan for you.

Preventing interactions

You can take certain steps to help prevent interactions with Entyvio. Your doctor and pharmacist are key resources, so reach out to them before starting treatment. For example, you should plan to do the following:

• Let them know if you drink alcohol or use cannabis.
• Tell them about any other medications you take, as well as any supplements, herbs, and vitamins.
• Create a medication list, which your doctor and pharmacist can help you fill out.

It’s also important to read the Entyvio label and other paperwork that may come with the drug. The label may have colored stickers that mention an interaction. And the paperwork, sometimes called the medication guide or patient package insert, may contain details about interactions.

If Entyvio doesn’t come with paperwork, you can ask your pharmacist to print a copy. If you need help reading or understanding this information, ask your doctor or pharmacist.

You can also help prevent interactions with Entyvio by taking it exactly as your doctor prescribes.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.