Analysis and practice on ethical, legal and social implications (ELSI) of science and technology increasingly requires co-operations between a variety of stakeholders and becomes more integrative with other frameworks including biosecurity and technology assessment (TA). These frameworks share a perspective on dynamic construction of technology and society by wider collaborations and networks. Against this backdrop, ideas and activities collectively dubbed as 'responsible research and innovation' (RRI) are developing particularly in the EU policy research context. RRI is concerned with the purposes of research and innovation while putting emphasis on the integration of established mechanisms of reflection and inclusive deliberation. As scientists can insist freedom of research only by taking response-ability to the society with its orientation to the future, ELSI and RRI are now required to facilitate collaborations of scientists and other various stakeholders and apportion responsibilities between the engaged individuals and their affiliations.