In ortho-substitution, two substituents occupy positions next to each other, which may be numbered 1 and 2. In the diagram, these positions are marked R and ortho.
In meta-substitution the substituents occupy positions 1 and 3 (corresponding to R and meta in the diagram).
In para-substitution, the substituents occupy the opposite ends (positions 1 and 4, corresponding to R and para in the diagram). The toluidines serve as an example for these three types of substitution.
Ipso, meso, and peri substitution
ipso- substitution.
ipso- substitution.
meso- substitution.
meso- substitution.
peri- substitution.
peri- substitution.
Ipso-substitution describes two substituents sharing the same ring position in an intermediate compound in an electrophilic aromatic substitution. Me3Si, t-Bu, and iPr groups can form stable carbocation, hence are ipso directing groups.
Norethisterone (INN, BAN), also known as norethindrone (USAN), as well as 19-nor-17α-ethynyltestosterone, but more commonly known under its trade name Utovlan® is a steroidalprogestin used in some combined oral contraceptive pills, progestogen only pills and is also available as a standalone drug. It can be used to treat premenstrual syndrome, painful periods, abnormal heavy bleeding, irregular periods, menopausal syndrome (in combination with estrogen), or to postpone a period. It is also commonly used to help prevent uterine hemorrhage in complicated non-surgical or pre-surgical gynecologic cases and in treating non responsive cyclical mastalgia. Norethisterone was the first orally highly active progestin to be synthesized. It was synthesized for the first time by chemists Luis Miramontes, Carl Djerassi, and George Rosenkranz at Syntex in Mexico City in 1951. It was the progestin used in one of the first three oral contraceptives. Its related ester, norethisterone acetate, is used for the same indications.
Orthopedic Surgeon Reacts to Dr. Glaucomflecken - Ortho Admits Patient to Medicine
In this video, Dr. Webb reacts to Dr. Glaucomflecken - Ortho Admits Patient to Medicine
Check out other reactions here:
https://youtube.com/playlist?list=PLAhk31i50Jpzp3mR5DcEh2VRummXw4Tia
Check out his original video here:
https://youtube.com/shorts/Vf0sH8nasNo?feature=share
To see Dr Webb as a patient, please contact:
Antonio J. Webb, MD
Orthopedic Spine Surgeon
South Texas Spinal Clinic
9150 Huebner Road Suite 290
San Antonio, Texas 78240
Office: 210-614-6432
Fax: 210-293-4171
www.spinaldoc.com
https://antoniowebbmd.com
Click below to be added to Dr. Webb's email list to be the first to be notified about what he is up to, pre-med and medical school advice, and general tips to be successful
https://mailchi.mp/bb18279302af/antoniowebbmd
Dr. Webb's Amazon Shopping List and Personal R...
published: 10 Mar 2022
Ortho Admits Patient To Medicine
published: 02 Dec 2021
Orthodontic Instruments
Various orthodontic instruments shown, named, and described.
Worksheet: https://drive.google.com/file/d/1a7AInFvBcgavCXUY0iW-AO6WcZVQ0B9T/view?usp=sharing
In this video, Dr. Webb reacts to Dr. Glaucomflecken - Ortho Admits Patient to Medicine
Check out other reactions here:
https://youtube.com/playlist?list=PLAhk...
In this video, Dr. Webb reacts to Dr. Glaucomflecken - Ortho Admits Patient to Medicine
Check out other reactions here:
https://youtube.com/playlist?list=PLAhk31i50Jpzp3mR5DcEh2VRummXw4Tia
Check out his original video here:
https://youtube.com/shorts/Vf0sH8nasNo?feature=share
To see Dr Webb as a patient, please contact:
Antonio J. Webb, MD
Orthopedic Spine Surgeon
South Texas Spinal Clinic
9150 Huebner Road Suite 290
San Antonio, Texas 78240
Office: 210-614-6432
Fax: 210-293-4171
www.spinaldoc.com
https://antoniowebbmd.com
Click below to be added to Dr. Webb's email list to be the first to be notified about what he is up to, pre-med and medical school advice, and general tips to be successful
https://mailchi.mp/bb18279302af/antoniowebbmd
Dr. Webb's Amazon Shopping List and Personal Recommendations: https://www.amazon.com/shop/antoniojwebbmd
Looking for a more personalized and 1:1 mentorship with Dr. Webb to help you reach your goals, then look no further!
Become a patreon and receive weekly or monthly phone calls from Dr. Webb, opportunity to have your application or personal statement reviewed, access to exclusive behind the scenes footage with never released pre-med/med/residency videos, personalized and proven to work study plans for the MCAT, USMLE step 1,2,and 3, and the chance to network with a physician in your career of choice plus more!
Become a patreon TODAY! Visit: https://www.patreon.com/overcomingtheodds
Book I Used to Do Well in Medical School
Constanza Physiology: http://amzn.to/2AYjVL6
Pathoma: http://amzn.to/2AYAM0a
USMLE Step 1 First Aid: http://amzn.to/2BkxQrU
BRS Physiology: http://amzn.to/2kC1FfD
BRS Biochemisry: http://amzn.to/2Bj5aQ3
BRS Gross Anatomy: http://amzn.to/2yKHzoo
BRS Cell Biology: http://amzn.to/2BkHf2s
BRS Pathology: http://amzn.to/2CJu3on
BRS Microbiology: http://amzn.to/2yKZTgZ
BRS Pharmacology: http://amzn.to/2j6B75L
BRS Embryology: http://amzn.to/2j8WPGq
Items I Used to Work Out & Stay Healthy in Med School
Harbinger Pro Wristwrap Weightlifting Gloves: http://amzn.to/2AX7K1c
Beats Studio Wireless Over-Ear Headphone (Matte Black) http://amzn.to/2k4973E
BlenderBottle Classic Loop Top Shaker Bottle: http://amzn.to/2k5orwM
Under Armour Men's Muscle Tank: http://amzn.to/2AWWP7H
Under Armour Men's Maverick Tapered Pants: http://amzn.to/2yKhyW6
Fitbit Charge Heart Rate + Fitness Wristband: http://amzn.to/2AWB73r
1/2-Inch Extra Thick Exercise Mat with Carrying Strap: http://amzn.to/2k3TaKy
What I Took To Stay Healthy While in Medical School!
GNC Pro Performance AMP Amplified Whey Protein: http://amzn.to/2yxwo35
Natural Vitality Organic Life Vitamins Liquid: http://amzn.to/2yAQBFj
Ninja Professional Blender: http://amzn.to/2AZhxUk
Fish Oil Concentrate with Omega-3 Fatty Acids: http://amzn.to/2AY2WIZ
Connect with Dr. Webb at:
https://linktr.ee/overcomingtheoddsbook
Connect with other pre med students, ask questions, receive advice and tips, connect with me at:
https://www.facebook.com/groups/soyouwanttobeadoctor
Dr. Webb's new book, Overcoming the Odds (ranked 5 STARS!) is available NOW at: http://amzn.to/2hV3MtR
MEDICAL DISCLAIMER
The information provided is not intended to be a substitute for professional medical advice, diagnosis or treatment. Never disregard professional medical advice, or delay in seeking it, because of something you have read on this website. Never rely on information on this website in place of seeking professional medical advice.
In this video, Dr. Webb reacts to Dr. Glaucomflecken - Ortho Admits Patient to Medicine
Check out other reactions here:
https://youtube.com/playlist?list=PLAhk31i50Jpzp3mR5DcEh2VRummXw4Tia
Check out his original video here:
https://youtube.com/shorts/Vf0sH8nasNo?feature=share
To see Dr Webb as a patient, please contact:
Antonio J. Webb, MD
Orthopedic Spine Surgeon
South Texas Spinal Clinic
9150 Huebner Road Suite 290
San Antonio, Texas 78240
Office: 210-614-6432
Fax: 210-293-4171
www.spinaldoc.com
https://antoniowebbmd.com
Click below to be added to Dr. Webb's email list to be the first to be notified about what he is up to, pre-med and medical school advice, and general tips to be successful
https://mailchi.mp/bb18279302af/antoniowebbmd
Dr. Webb's Amazon Shopping List and Personal Recommendations: https://www.amazon.com/shop/antoniojwebbmd
Looking for a more personalized and 1:1 mentorship with Dr. Webb to help you reach your goals, then look no further!
Become a patreon and receive weekly or monthly phone calls from Dr. Webb, opportunity to have your application or personal statement reviewed, access to exclusive behind the scenes footage with never released pre-med/med/residency videos, personalized and proven to work study plans for the MCAT, USMLE step 1,2,and 3, and the chance to network with a physician in your career of choice plus more!
Become a patreon TODAY! Visit: https://www.patreon.com/overcomingtheodds
Book I Used to Do Well in Medical School
Constanza Physiology: http://amzn.to/2AYjVL6
Pathoma: http://amzn.to/2AYAM0a
USMLE Step 1 First Aid: http://amzn.to/2BkxQrU
BRS Physiology: http://amzn.to/2kC1FfD
BRS Biochemisry: http://amzn.to/2Bj5aQ3
BRS Gross Anatomy: http://amzn.to/2yKHzoo
BRS Cell Biology: http://amzn.to/2BkHf2s
BRS Pathology: http://amzn.to/2CJu3on
BRS Microbiology: http://amzn.to/2yKZTgZ
BRS Pharmacology: http://amzn.to/2j6B75L
BRS Embryology: http://amzn.to/2j8WPGq
Items I Used to Work Out & Stay Healthy in Med School
Harbinger Pro Wristwrap Weightlifting Gloves: http://amzn.to/2AX7K1c
Beats Studio Wireless Over-Ear Headphone (Matte Black) http://amzn.to/2k4973E
BlenderBottle Classic Loop Top Shaker Bottle: http://amzn.to/2k5orwM
Under Armour Men's Muscle Tank: http://amzn.to/2AWWP7H
Under Armour Men's Maverick Tapered Pants: http://amzn.to/2yKhyW6
Fitbit Charge Heart Rate + Fitness Wristband: http://amzn.to/2AWB73r
1/2-Inch Extra Thick Exercise Mat with Carrying Strap: http://amzn.to/2k3TaKy
What I Took To Stay Healthy While in Medical School!
GNC Pro Performance AMP Amplified Whey Protein: http://amzn.to/2yxwo35
Natural Vitality Organic Life Vitamins Liquid: http://amzn.to/2yAQBFj
Ninja Professional Blender: http://amzn.to/2AZhxUk
Fish Oil Concentrate with Omega-3 Fatty Acids: http://amzn.to/2AY2WIZ
Connect with Dr. Webb at:
https://linktr.ee/overcomingtheoddsbook
Connect with other pre med students, ask questions, receive advice and tips, connect with me at:
https://www.facebook.com/groups/soyouwanttobeadoctor
Dr. Webb's new book, Overcoming the Odds (ranked 5 STARS!) is available NOW at: http://amzn.to/2hV3MtR
MEDICAL DISCLAIMER
The information provided is not intended to be a substitute for professional medical advice, diagnosis or treatment. Never disregard professional medical advice, or delay in seeking it, because of something you have read on this website. Never rely on information on this website in place of seeking professional medical advice.
Various orthodontic instruments shown, named, and described.
Worksheet: https://drive.google.com/file/d/1a7AInFvBcgavCXUY0iW-AO6WcZVQ0B9T/view?usp=sharing
Various orthodontic instruments shown, named, and described.
Worksheet: https://drive.google.com/file/d/1a7AInFvBcgavCXUY0iW-AO6WcZVQ0B9T/view?usp=sharing
Various orthodontic instruments shown, named, and described.
Worksheet: https://drive.google.com/file/d/1a7AInFvBcgavCXUY0iW-AO6WcZVQ0B9T/view?usp=sharing
In this video, Dr. Webb reacts to Dr. Glaucomflecken - Ortho Admits Patient to Medicine
Check out other reactions here:
https://youtube.com/playlist?list=PLAhk31i50Jpzp3mR5DcEh2VRummXw4Tia
Check out his original video here:
https://youtube.com/shorts/Vf0sH8nasNo?feature=share
To see Dr Webb as a patient, please contact:
Antonio J. Webb, MD
Orthopedic Spine Surgeon
South Texas Spinal Clinic
9150 Huebner Road Suite 290
San Antonio, Texas 78240
Office: 210-614-6432
Fax: 210-293-4171
www.spinaldoc.com
https://antoniowebbmd.com
Click below to be added to Dr. Webb's email list to be the first to be notified about what he is up to, pre-med and medical school advice, and general tips to be successful
https://mailchi.mp/bb18279302af/antoniowebbmd
Dr. Webb's Amazon Shopping List and Personal Recommendations: https://www.amazon.com/shop/antoniojwebbmd
Looking for a more personalized and 1:1 mentorship with Dr. Webb to help you reach your goals, then look no further!
Become a patreon and receive weekly or monthly phone calls from Dr. Webb, opportunity to have your application or personal statement reviewed, access to exclusive behind the scenes footage with never released pre-med/med/residency videos, personalized and proven to work study plans for the MCAT, USMLE step 1,2,and 3, and the chance to network with a physician in your career of choice plus more!
Become a patreon TODAY! Visit: https://www.patreon.com/overcomingtheodds
Book I Used to Do Well in Medical School
Constanza Physiology: http://amzn.to/2AYjVL6
Pathoma: http://amzn.to/2AYAM0a
USMLE Step 1 First Aid: http://amzn.to/2BkxQrU
BRS Physiology: http://amzn.to/2kC1FfD
BRS Biochemisry: http://amzn.to/2Bj5aQ3
BRS Gross Anatomy: http://amzn.to/2yKHzoo
BRS Cell Biology: http://amzn.to/2BkHf2s
BRS Pathology: http://amzn.to/2CJu3on
BRS Microbiology: http://amzn.to/2yKZTgZ
BRS Pharmacology: http://amzn.to/2j6B75L
BRS Embryology: http://amzn.to/2j8WPGq
Items I Used to Work Out & Stay Healthy in Med School
Harbinger Pro Wristwrap Weightlifting Gloves: http://amzn.to/2AX7K1c
Beats Studio Wireless Over-Ear Headphone (Matte Black) http://amzn.to/2k4973E
BlenderBottle Classic Loop Top Shaker Bottle: http://amzn.to/2k5orwM
Under Armour Men's Muscle Tank: http://amzn.to/2AWWP7H
Under Armour Men's Maverick Tapered Pants: http://amzn.to/2yKhyW6
Fitbit Charge Heart Rate + Fitness Wristband: http://amzn.to/2AWB73r
1/2-Inch Extra Thick Exercise Mat with Carrying Strap: http://amzn.to/2k3TaKy
What I Took To Stay Healthy While in Medical School!
GNC Pro Performance AMP Amplified Whey Protein: http://amzn.to/2yxwo35
Natural Vitality Organic Life Vitamins Liquid: http://amzn.to/2yAQBFj
Ninja Professional Blender: http://amzn.to/2AZhxUk
Fish Oil Concentrate with Omega-3 Fatty Acids: http://amzn.to/2AY2WIZ
Connect with Dr. Webb at:
https://linktr.ee/overcomingtheoddsbook
Connect with other pre med students, ask questions, receive advice and tips, connect with me at:
https://www.facebook.com/groups/soyouwanttobeadoctor
Dr. Webb's new book, Overcoming the Odds (ranked 5 STARS!) is available NOW at: http://amzn.to/2hV3MtR
MEDICAL DISCLAIMER
The information provided is not intended to be a substitute for professional medical advice, diagnosis or treatment. Never disregard professional medical advice, or delay in seeking it, because of something you have read on this website. Never rely on information on this website in place of seeking professional medical advice.
Various orthodontic instruments shown, named, and described.
Worksheet: https://drive.google.com/file/d/1a7AInFvBcgavCXUY0iW-AO6WcZVQ0B9T/view?usp=sharing
In ortho-substitution, two substituents occupy positions next to each other, which may be numbered 1 and 2. In the diagram, these positions are marked R and ortho.
In meta-substitution the substituents occupy positions 1 and 3 (corresponding to R and meta in the diagram).
In para-substitution, the substituents occupy the opposite ends (positions 1 and 4, corresponding to R and para in the diagram). The toluidines serve as an example for these three types of substitution.
Ipso, meso, and peri substitution
ipso- substitution.
ipso- substitution.
meso- substitution.
meso- substitution.
peri- substitution.
peri- substitution.
Ipso-substitution describes two substituents sharing the same ring position in an intermediate compound in an electrophilic aromatic substitution. Me3Si, t-Bu, and iPr groups can form stable carbocation, hence are ipso directing groups.
"Counter to this dogma, Jose demonstrated that using B2Pin2 as the boron source affords meta selective chemistry while using HBPin as the boron source gives ortho selective borylation using the same iPrACNCCo catalyst.
The article is titled “Five-membered ring compounds from the ortho-benzyne + methyl radical reaction under interstellar conditions” and is published in the journal NatureAstronomy... In nature, chemistry evolved over time.
The team's findings hinge on a deceptively simple molecule called ortho-benzyne ... Ortho-benzyne, in other words, seems to be a prime candidate for driving the gas-phase organic chemistry that occurs within these stellar nurseries, Bouwman said.
"In principle, substituted aromatic compounds have three positions to which a catalyst can attach in order to induce a reaction—called ortho, meta and para ... of OrganicChemistry at Kiel University.
... of Chemistry and Biochemistry at Baylor University and principal investigator of the Martin Research Group, and his team have developed a new compound known as tris(ortho-carboranyl)borane or BoCb3.