-
Medical vocabulary: What does Glutamate-Cysteine Ligase mean
What does Glutamate-Cysteine Ligase mean in English?
published: 17 Jan 2016
-
Glutathione Detox: The Science of Glutathione and Alcohol – Thomas DeLauer
Glutathione Detox: The Science of Glutathione and Alcohol – Thomas DeLauer…
Your body can have its own glutathione detox! Glutathione and Alcohol is a huge question, how does it actually work? More at http://www.thomasdelauer.com
What is Glutathione? Glutathione (GSH) is a peptide made up of three amino acids - glutamic acid, cysteine and glycine. GSH is produced by every cell in our bodies. It is an antioxidant that works within cells. Aerobic cells in our body require oxygen. During the cellular processes that occur, ROS (reactive oxygen species) occur. When cells are injured even more ROS will be produced. ROS are not always bad. They are necessary for cell survival, but when there are too many produced it can lead to cell damage and death. When the levels of ROS raise, our bodies work...
published: 12 Nov 2016
-
글루타치온을 만드는 효소 GCL Glutamate Cysteine Ligase. 그럼 GCL를 만드는 것은?
글루타치온의 생성을 결정 짖는 효소: GCL glutamate cysteine ligase 글루탐산 시스테인 연결 효소. 글루타치온을 몸에서 만드는 것은 김밥을 만드는 것과 같습니다
NRF2를 활성화 시키는 방법은 다양합니다.
- 설포라판
- 강도 높은 운동
- 소식 / 단식
published: 20 Sep 2023
-
How is Glutathione produced in the body?
Associate Professor Wallace Bridge, UNSW Sydney explains to Bernie Landes of Nutritional Products Consulting Group how glutathione is produced in every cell of our bodies.
The system involves two enzymes (catalysts) that sequentially join the three amino acids glutamate, cysteine and glycine to form glutathione. The first enzyme (glutamate cysteine ligase, GCL) joins glutamate and cysteine to form gamma glutamylcysteine (GGC, Glyteine™️) and the second enzyme glutathione synthetase adds the glycine to make glutathione.
Both these reactions require energy (ATP), which is provided on the most part by the mitochondria. They then go on to discuss how glutathione levels are maintained (regulated) in cells at optimum (homeostasis) levels and the implications if this system goes wrong.
T...
published: 12 Sep 2019
-
Glutamate–cysteine ligase - Wikipedia Article Audio
For more information, please, visit: https://a.webull.com/KJLOK7GVRt9ngH7iql This is an audio version of a Wikipedia article created for the benefit of those who have vision problems or problem reading at night. This Wikipedia article audio was created under Creative Commons Attribution-ShareAlike. To view the original article, go to https://en.wikipedia.org/wiki/[AUDIO_TITLE].
published: 31 May 2018
-
Glutamine Synthesis
published: 08 Feb 2021
-
Gene Music using Protein Sequence of GCLM "GLUTAMATE-CYSTEINE LIGASE, MODIFIER SUBUNIT"
Shop GCLM - https://www.redbubble.com/people/genemusic/works/45678960-gclm?asc=u
Subscribe - https://www.youtube.com/c/GeneMusicStudio?sub_confirmation=1
Gene Music Studio - A channel to taste (visually & musically) gene information (particularly protein sequences)
Gene Music using Protein Sequence of GCLM 'GLUTAMATE-CYSTEINE LIGASE, MODIFIER SUBUNIT'
published: 12 Sep 2016
-
NAC for Mould Detox? Think Again!
TREAT DIGESTION NATURALLY! To find out more see our bookings page here: https://www.byronherbalist.com.au/appointments/
My name is Todd Mansfield and I’m a clinical herbalist dedicated to digestive health. Every week I treat Australian and New Zealand patients with IBS, IBD, SIBO, reflux, indigestion, bloating, loose bowel movements and constipation.
Follow my work here: https://www.instagram.com/byron.herbalist/
For everyone else, I’m passionate about supporting you so follow along with this free content to support your digestion without drugs!
----------------------------------------------------------------------------------------------------------------------
An important aspect that often gets overlooked when we're discussing mould detox protocols is highlighted by the organic ...
published: 27 Aug 2023
-
Conversion Of Amino Acids To Special Products (Creatine,Glutathione And Nitric Oxide) Biochemistry.
Special Products/compounds Derived From Certain Amino Acids ; The Biochemistry Of Creatine,Glutathione And Nitric Oxide.This Video Highlights The Formation/biosynthesis , Formation Pathway And The A Few Main Functions Of The Compounds/Products Formed From Amino Acids.
How Creatine is Formed In Brain And Muscle Cells ?; How The Body's Master Antioxidant Is Synthesized in The Body ?; and What Is The Endothelium Derived Relaxation Factor ?
This video Explains The Answers Of Such these Questions.
******************************************************************************
Amino Acids Can be Converted into Certain Products. These Special Products Can Be Creatine,Glutathione And Nitric Oxide.
Creatine ;-
Creatine Is The Compound That Is Derived From Amino Acids Glycine,Arginine And S-Adenosylm...
published: 08 Aug 2020
-
How does low Glutathione levels lead to oxidative stress?
Associate Professor Wallace Bridge, UNSW Sydney and Bernie Landes of Nutritional Products Consulting Group discuss glutathione depletion and oxidative stress. Repeated exposure to oxidative stress can result in an accumulation of permanent damage to cells and their progeny.
In many diseases and disorders, the first enzyme (glutamate cysteine ligase) involved in the synthesis of glutathione becomes dysfunctional and maintains glutathione (homeostasis) at levels too low to protect against oxidative stress.
Bernie ponders whether accumulated oxidative stress damage may actually be one of the causes of this enzyme dysfunction with Wallace commenting that the nature of how the enzyme becomes dysfunctional is the subject of ongoing research.
To know more visit us on https://www.continualg.co...
published: 12 Sep 2019
9:57
Glutathione Detox: The Science of Glutathione and Alcohol – Thomas DeLauer
Glutathione Detox: The Science of Glutathione and Alcohol – Thomas DeLauer…
Your body can have its own glutathione detox! Glutathione and Alcohol is a huge que...
Glutathione Detox: The Science of Glutathione and Alcohol – Thomas DeLauer…
Your body can have its own glutathione detox! Glutathione and Alcohol is a huge question, how does it actually work? More at http://www.thomasdelauer.com
What is Glutathione? Glutathione (GSH) is a peptide made up of three amino acids - glutamic acid, cysteine and glycine. GSH is produced by every cell in our bodies. It is an antioxidant that works within cells. Aerobic cells in our body require oxygen. During the cellular processes that occur, ROS (reactive oxygen species) occur. When cells are injured even more ROS will be produced. ROS are not always bad. They are necessary for cell survival, but when there are too many produced it can lead to cell damage and death. When the levels of ROS raise, our bodies work to balance this out and regain homeostasis through the production of antioxidants, such as GSH.
GSH:
-Protects against oxidative damage and environmental toxins
-Disposes peroxides (natural bleaching agents that cause harm in the body)
-Participates in metabolic processes
-Maintains intracellular health
-Boosts immune system
Due to its properties, GSH:
-Protects brain health
-Protects liver and other organs from damage
-May protect against many other diseases due to cell damage, including Alzheimer’s, cancers and AIDs
It has been found that most patients in the hospitals for conditions such as cancer and AIDs have depleted GSH levels. So what are the ways that we understand presently that GSH benefits our health?
Brain Health: The cells of the brain make up 2% of our body weight while consuming 20% of the oxygen used in the body. The makes brain cells particularly at risk to oxidative damage. GSH is important in the detoxification processes of reactive oxygen species in the brain. Under normal conditions GSH synthesis is determined by cysteine availability and the activity of an enzyme called GCL (glutamate-cysteine ligase). Cysteine comes from the diet, protein breakdown and the liver. The amount of GSH present in the brain is dependent upon how much of the precursors are present. Different kinds of brain cells require different precursors.
Liver: Helps the liver remove chemicals, such as drugs and environmental toxins. Glutathione is produced by the liver in response to alcohol consumption. When alcohol comes into contact with enzymes in your mouth, Acetaldehyde forms. Acetaldehyde is extremely toxic. When the remainder of the alcohol reaches your liver, it is processed into Acetaldehyde and your liver produces glutathione, which attacks the acetaldehyde to form a non-toxic substance similar to vinegar.
Cancer: Oxidative stress can lead to cancer, and GSH can help protect against oxidative stress. This is how GSH can help to protect your body from cancer. There is an instance where medical professionals may desire to reduce the GSH in your cells, and that is when fighting cancer cells with chemotherapy. High GSH levels in tumor cells can make them difficult to fight. There is other evidence that GSH supplementation may help to reduce chemotherapy side effects and thus make it more effective, so this is currently under debate.
How to Get Enough GSH: While studies have shown that elevated GSH levels can benefit health, exactly how to boost these levels is still debated. Supplements have not been proven to be an effective way to boost cellular GSH. Intravenous GSH was shown in one study to boost the survival rates and decrease the side effects from chemotherapy in women with ovarian cancer. It is likely that taking precursor supplements of cysteine may boost GSH levels. A balanced diet is the key to healthy GSH levels - fresh fruits, veggies and meats.
2 supplements that help boost GSH levels are:
-Milk thistle
-Whey protein
References:
1. Metabolism and functions of glutathione in the brain
https://www.ncbi.nlm.nih.gov/pubmed/10880854
2. Role of glutathione in cancer progression and chemoresistance
https://www.hindawi.com/journals/omcl/2013/972913/
3. Glutathione: new supplement on the block
http://www.medicinenet.com/script/main/art.asp?articlekey=50746
4. Protective effects of silymarin, a milk thistle…
https://www.ncbi.nlm.nih.gov/pubmed/17133738
5. Oral supplementation with whey protein increases plasma glutathione…
https://www.ncbi.nlm.nih.gov/pubmed/11168457
6. Glutathione and sulphur amino acids in health and human disease
http://www.wiley.com/WileyCDA/WileyTitle/productCd-0470170859.html
https://wn.com/Glutathione_Detox_The_Science_Of_Glutathione_And_Alcohol_–_Thomas_Delauer
Glutathione Detox: The Science of Glutathione and Alcohol – Thomas DeLauer…
Your body can have its own glutathione detox! Glutathione and Alcohol is a huge question, how does it actually work? More at http://www.thomasdelauer.com
What is Glutathione? Glutathione (GSH) is a peptide made up of three amino acids - glutamic acid, cysteine and glycine. GSH is produced by every cell in our bodies. It is an antioxidant that works within cells. Aerobic cells in our body require oxygen. During the cellular processes that occur, ROS (reactive oxygen species) occur. When cells are injured even more ROS will be produced. ROS are not always bad. They are necessary for cell survival, but when there are too many produced it can lead to cell damage and death. When the levels of ROS raise, our bodies work to balance this out and regain homeostasis through the production of antioxidants, such as GSH.
GSH:
-Protects against oxidative damage and environmental toxins
-Disposes peroxides (natural bleaching agents that cause harm in the body)
-Participates in metabolic processes
-Maintains intracellular health
-Boosts immune system
Due to its properties, GSH:
-Protects brain health
-Protects liver and other organs from damage
-May protect against many other diseases due to cell damage, including Alzheimer’s, cancers and AIDs
It has been found that most patients in the hospitals for conditions such as cancer and AIDs have depleted GSH levels. So what are the ways that we understand presently that GSH benefits our health?
Brain Health: The cells of the brain make up 2% of our body weight while consuming 20% of the oxygen used in the body. The makes brain cells particularly at risk to oxidative damage. GSH is important in the detoxification processes of reactive oxygen species in the brain. Under normal conditions GSH synthesis is determined by cysteine availability and the activity of an enzyme called GCL (glutamate-cysteine ligase). Cysteine comes from the diet, protein breakdown and the liver. The amount of GSH present in the brain is dependent upon how much of the precursors are present. Different kinds of brain cells require different precursors.
Liver: Helps the liver remove chemicals, such as drugs and environmental toxins. Glutathione is produced by the liver in response to alcohol consumption. When alcohol comes into contact with enzymes in your mouth, Acetaldehyde forms. Acetaldehyde is extremely toxic. When the remainder of the alcohol reaches your liver, it is processed into Acetaldehyde and your liver produces glutathione, which attacks the acetaldehyde to form a non-toxic substance similar to vinegar.
Cancer: Oxidative stress can lead to cancer, and GSH can help protect against oxidative stress. This is how GSH can help to protect your body from cancer. There is an instance where medical professionals may desire to reduce the GSH in your cells, and that is when fighting cancer cells with chemotherapy. High GSH levels in tumor cells can make them difficult to fight. There is other evidence that GSH supplementation may help to reduce chemotherapy side effects and thus make it more effective, so this is currently under debate.
How to Get Enough GSH: While studies have shown that elevated GSH levels can benefit health, exactly how to boost these levels is still debated. Supplements have not been proven to be an effective way to boost cellular GSH. Intravenous GSH was shown in one study to boost the survival rates and decrease the side effects from chemotherapy in women with ovarian cancer. It is likely that taking precursor supplements of cysteine may boost GSH levels. A balanced diet is the key to healthy GSH levels - fresh fruits, veggies and meats.
2 supplements that help boost GSH levels are:
-Milk thistle
-Whey protein
References:
1. Metabolism and functions of glutathione in the brain
https://www.ncbi.nlm.nih.gov/pubmed/10880854
2. Role of glutathione in cancer progression and chemoresistance
https://www.hindawi.com/journals/omcl/2013/972913/
3. Glutathione: new supplement on the block
http://www.medicinenet.com/script/main/art.asp?articlekey=50746
4. Protective effects of silymarin, a milk thistle…
https://www.ncbi.nlm.nih.gov/pubmed/17133738
5. Oral supplementation with whey protein increases plasma glutathione…
https://www.ncbi.nlm.nih.gov/pubmed/11168457
6. Glutathione and sulphur amino acids in health and human disease
http://www.wiley.com/WileyCDA/WileyTitle/productCd-0470170859.html
- published: 12 Nov 2016
- views: 269604
2:29
글루타치온을 만드는 효소 GCL Glutamate Cysteine Ligase. 그럼 GCL를 만드는 것은?
글루타치온의 생성을 결정 짖는 효소: GCL glutamate cysteine ligase 글루탐산 시스테인 연결 효소. 글루타치온을 몸에서 만드는 것은 김밥을 만드는 것과 같습니다
NRF2를 활성화 시키는 방법은 다양합니다.
- 설포라판
- 강도 높은 운동
- 소식 / 단식...
글루타치온의 생성을 결정 짖는 효소: GCL glutamate cysteine ligase 글루탐산 시스테인 연결 효소. 글루타치온을 몸에서 만드는 것은 김밥을 만드는 것과 같습니다
NRF2를 활성화 시키는 방법은 다양합니다.
- 설포라판
- 강도 높은 운동
- 소식 / 단식
https://wn.com/글루타치온을_만드는_효소_Gcl_Glutamate_Cysteine_Ligase._그럼_Gcl를_만드는_것은
글루타치온의 생성을 결정 짖는 효소: GCL glutamate cysteine ligase 글루탐산 시스테인 연결 효소. 글루타치온을 몸에서 만드는 것은 김밥을 만드는 것과 같습니다
NRF2를 활성화 시키는 방법은 다양합니다.
- 설포라판
- 강도 높은 운동
- 소식 / 단식
- published: 20 Sep 2023
- views: 99
5:10
How is Glutathione produced in the body?
Associate Professor Wallace Bridge, UNSW Sydney explains to Bernie Landes of Nutritional Products Consulting Group how glutathione is produced in every cell of ...
Associate Professor Wallace Bridge, UNSW Sydney explains to Bernie Landes of Nutritional Products Consulting Group how glutathione is produced in every cell of our bodies.
The system involves two enzymes (catalysts) that sequentially join the three amino acids glutamate, cysteine and glycine to form glutathione. The first enzyme (glutamate cysteine ligase, GCL) joins glutamate and cysteine to form gamma glutamylcysteine (GGC, Glyteine™️) and the second enzyme glutathione synthetase adds the glycine to make glutathione.
Both these reactions require energy (ATP), which is provided on the most part by the mitochondria. They then go on to discuss how glutathione levels are maintained (regulated) in cells at optimum (homeostasis) levels and the implications if this system goes wrong.
To know more visit us on https://www.continualg.com
https://wn.com/How_Is_Glutathione_Produced_In_The_Body
Associate Professor Wallace Bridge, UNSW Sydney explains to Bernie Landes of Nutritional Products Consulting Group how glutathione is produced in every cell of our bodies.
The system involves two enzymes (catalysts) that sequentially join the three amino acids glutamate, cysteine and glycine to form glutathione. The first enzyme (glutamate cysteine ligase, GCL) joins glutamate and cysteine to form gamma glutamylcysteine (GGC, Glyteine™️) and the second enzyme glutathione synthetase adds the glycine to make glutathione.
Both these reactions require energy (ATP), which is provided on the most part by the mitochondria. They then go on to discuss how glutathione levels are maintained (regulated) in cells at optimum (homeostasis) levels and the implications if this system goes wrong.
To know more visit us on https://www.continualg.com
- published: 12 Sep 2019
- views: 4700
6:56
Glutamate–cysteine ligase - Wikipedia Article Audio
For more information, please, visit: https://a.webull.com/KJLOK7GVRt9ngH7iql This is an audio version of a Wikipedia article created for the benefit of those wh...
For more information, please, visit: https://a.webull.com/KJLOK7GVRt9ngH7iql This is an audio version of a Wikipedia article created for the benefit of those who have vision problems or problem reading at night. This Wikipedia article audio was created under Creative Commons Attribution-ShareAlike. To view the original article, go to https://en.wikipedia.org/wiki/[AUDIO_TITLE].
https://wn.com/Glutamate–Cysteine_Ligase_Wikipedia_Article_Audio
For more information, please, visit: https://a.webull.com/KJLOK7GVRt9ngH7iql This is an audio version of a Wikipedia article created for the benefit of those who have vision problems or problem reading at night. This Wikipedia article audio was created under Creative Commons Attribution-ShareAlike. To view the original article, go to https://en.wikipedia.org/wiki/[AUDIO_TITLE].
- published: 31 May 2018
- views: 17
1:11
Gene Music using Protein Sequence of GCLM "GLUTAMATE-CYSTEINE LIGASE, MODIFIER SUBUNIT"
Shop GCLM - https://www.redbubble.com/people/genemusic/works/45678960-gclm?asc=u
Subscribe - https://www.youtube.com/c/GeneMusicStudio?sub_confirmation=1
Gene M...
Shop GCLM - https://www.redbubble.com/people/genemusic/works/45678960-gclm?asc=u
Subscribe - https://www.youtube.com/c/GeneMusicStudio?sub_confirmation=1
Gene Music Studio - A channel to taste (visually & musically) gene information (particularly protein sequences)
Gene Music using Protein Sequence of GCLM 'GLUTAMATE-CYSTEINE LIGASE, MODIFIER SUBUNIT'
https://wn.com/Gene_Music_Using_Protein_Sequence_Of_Gclm_Glutamate_Cysteine_Ligase,_Modifier_Subunit
Shop GCLM - https://www.redbubble.com/people/genemusic/works/45678960-gclm?asc=u
Subscribe - https://www.youtube.com/c/GeneMusicStudio?sub_confirmation=1
Gene Music Studio - A channel to taste (visually & musically) gene information (particularly protein sequences)
Gene Music using Protein Sequence of GCLM 'GLUTAMATE-CYSTEINE LIGASE, MODIFIER SUBUNIT'
- published: 12 Sep 2016
- views: 82
1:00
NAC for Mould Detox? Think Again!
TREAT DIGESTION NATURALLY! To find out more see our bookings page here: https://www.byronherbalist.com.au/appointments/
My name is Todd Mansfield and I’m a cl...
TREAT DIGESTION NATURALLY! To find out more see our bookings page here: https://www.byronherbalist.com.au/appointments/
My name is Todd Mansfield and I’m a clinical herbalist dedicated to digestive health. Every week I treat Australian and New Zealand patients with IBS, IBD, SIBO, reflux, indigestion, bloating, loose bowel movements and constipation.
Follow my work here: https://www.instagram.com/byron.herbalist/
For everyone else, I’m passionate about supporting you so follow along with this free content to support your digestion without drugs!
----------------------------------------------------------------------------------------------------------------------
An important aspect that often gets overlooked when we're discussing mould detox protocols is highlighted by the organic acid test. Many of these mould affected patients are struggling to synthesise sufficient levels of glutathione. Consider supplementation with liposomal glutathione but keep in mind that it can be highly reactivity and poorly tolerated in some. Initial doses should be conservative, as some individuals might not tolerate it well.
A bunch of mould affected people come to me already supplementing with NAC as a good cheap precursor to glutathione but I have concerns around the conversion of NAC down to glutathione here. There is some evidence to show that the GCL enzyme (glutamate-cysteine ligase) gets downregulated with mycotoxins in the body.
In the context of mycotoxin-related mold exposure, the effectiveness of this approach might be reduced.
https://wn.com/Nac_For_Mould_Detox_Think_Again
TREAT DIGESTION NATURALLY! To find out more see our bookings page here: https://www.byronherbalist.com.au/appointments/
My name is Todd Mansfield and I’m a clinical herbalist dedicated to digestive health. Every week I treat Australian and New Zealand patients with IBS, IBD, SIBO, reflux, indigestion, bloating, loose bowel movements and constipation.
Follow my work here: https://www.instagram.com/byron.herbalist/
For everyone else, I’m passionate about supporting you so follow along with this free content to support your digestion without drugs!
----------------------------------------------------------------------------------------------------------------------
An important aspect that often gets overlooked when we're discussing mould detox protocols is highlighted by the organic acid test. Many of these mould affected patients are struggling to synthesise sufficient levels of glutathione. Consider supplementation with liposomal glutathione but keep in mind that it can be highly reactivity and poorly tolerated in some. Initial doses should be conservative, as some individuals might not tolerate it well.
A bunch of mould affected people come to me already supplementing with NAC as a good cheap precursor to glutathione but I have concerns around the conversion of NAC down to glutathione here. There is some evidence to show that the GCL enzyme (glutamate-cysteine ligase) gets downregulated with mycotoxins in the body.
In the context of mycotoxin-related mold exposure, the effectiveness of this approach might be reduced.
- published: 27 Aug 2023
- views: 2712
8:32
Conversion Of Amino Acids To Special Products (Creatine,Glutathione And Nitric Oxide) Biochemistry.
Special Products/compounds Derived From Certain Amino Acids ; The Biochemistry Of Creatine,Glutathione And Nitric Oxide.This Video Highlights The Formation/bios...
Special Products/compounds Derived From Certain Amino Acids ; The Biochemistry Of Creatine,Glutathione And Nitric Oxide.This Video Highlights The Formation/biosynthesis , Formation Pathway And The A Few Main Functions Of The Compounds/Products Formed From Amino Acids.
How Creatine is Formed In Brain And Muscle Cells ?; How The Body's Master Antioxidant Is Synthesized in The Body ?; and What Is The Endothelium Derived Relaxation Factor ?
This video Explains The Answers Of Such these Questions.
******************************************************************************
Amino Acids Can be Converted into Certain Products. These Special Products Can Be Creatine,Glutathione And Nitric Oxide.
Creatine ;-
Creatine Is The Compound That Is Derived From Amino Acids Glycine,Arginine And S-Adenosylmethionine Whithin The Liver.
It Is Present In High Concentration In Muscle And Brain Tissue.
} It Provides A Small Reservoir Of High Energy Phosphate Specially During Early Stages Of Exercise.
Glutathione ;-
Glutathione is A Tripeptide (Composed Of Amino Acids Cysteine,Glycine And
Glutamate) Synthesized By Sequential Addition Of Cysteine To Glutamate Followed By Addition Of Glycine.
~ It Is Biosynthesized By Two ATP dependent Steps Catalyzed By GLC (Glutamate Cysteine Ligase) And GS ( Glutathione Synthase ) Enzymes.
~ Glutathione Is The Body's Master Andioxidant , It Protect The Body From Reducing Agents.
Nitric Oxide ;-
A Amino Acid Derivate Nitric Oxide Is Formed During The Conversion of Arginine To Citrulline.
The Synthesis Reaction Is Carried By Nitric Oxide Synthase Enzyme.
~ Nitric Oxide Is The Endothelium Derived Relaxation Factor ; It Stimulates The Influx Of Ca+ into Vascular Endothelial Cells That Result In Relaxation Of Vascular Smooth Muscles.
******************************************************************************
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
Synthesis Of Amino Acids ; Precursors & Reaction Steps (Summary) | Medico Star.
https://youtu.be/ogFJ2l4eMvM
Phenylketonuria (Metabolic Disorder Of Phenylalanine) Its Cause, Symptoms,Diagnose And Treatments.
https://youtu.be/5hs-A0KNVy0
Alkaptonuria(Black Urine Disease) Its Cause, Symptoms,Diagnose And Treatments | Medico Star.
https://youtu.be/tn9DAVqjbaw
Complications Of Diabetes ; Microvascular & Macrovascular Complications Of Diabetes | Medico Star.
https://youtu.be/QVAX2b54pQ0
What Does De Novo Synthesis mean ? Examples. | Medico Star.
https://youtu.be/eyP6j0P4GZE
Carnitine Deficinecy ; Its Cause, Types And Symptoms. Complete Concept To Remember.| Medico Star.
https://youtu.be/BMLb2GX6jjk
What Is Saliva? Its Composition And Secretion Types Of Saliva ; Salivary Glands | Medico Star.
https://youtu.be/QvgqJB5z328
How Gastric Mucosa Is Protected? The Protective Mechanism Of Gastric Mucosa | Medico Star.
https://youtu.be/djK-UGRYbA4
!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
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Welcome To My Channel = " #MedicoStar "=.
*All the Knowledge Regarding Medical Study.*
Like Share This Video And
Do SUBSCRIBE My Channel For More Videos..+++.
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https://wn.com/Conversion_Of_Amino_Acids_To_Special_Products_(Creatine,Glutathione_And_Nitric_Oxide)_Biochemistry.
Special Products/compounds Derived From Certain Amino Acids ; The Biochemistry Of Creatine,Glutathione And Nitric Oxide.This Video Highlights The Formation/biosynthesis , Formation Pathway And The A Few Main Functions Of The Compounds/Products Formed From Amino Acids.
How Creatine is Formed In Brain And Muscle Cells ?; How The Body's Master Antioxidant Is Synthesized in The Body ?; and What Is The Endothelium Derived Relaxation Factor ?
This video Explains The Answers Of Such these Questions.
******************************************************************************
Amino Acids Can be Converted into Certain Products. These Special Products Can Be Creatine,Glutathione And Nitric Oxide.
Creatine ;-
Creatine Is The Compound That Is Derived From Amino Acids Glycine,Arginine And S-Adenosylmethionine Whithin The Liver.
It Is Present In High Concentration In Muscle And Brain Tissue.
} It Provides A Small Reservoir Of High Energy Phosphate Specially During Early Stages Of Exercise.
Glutathione ;-
Glutathione is A Tripeptide (Composed Of Amino Acids Cysteine,Glycine And
Glutamate) Synthesized By Sequential Addition Of Cysteine To Glutamate Followed By Addition Of Glycine.
~ It Is Biosynthesized By Two ATP dependent Steps Catalyzed By GLC (Glutamate Cysteine Ligase) And GS ( Glutathione Synthase ) Enzymes.
~ Glutathione Is The Body's Master Andioxidant , It Protect The Body From Reducing Agents.
Nitric Oxide ;-
A Amino Acid Derivate Nitric Oxide Is Formed During The Conversion of Arginine To Citrulline.
The Synthesis Reaction Is Carried By Nitric Oxide Synthase Enzyme.
~ Nitric Oxide Is The Endothelium Derived Relaxation Factor ; It Stimulates The Influx Of Ca+ into Vascular Endothelial Cells That Result In Relaxation Of Vascular Smooth Muscles.
******************************************************************************
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
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- published: 08 Aug 2020
- views: 3511
1:26
How does low Glutathione levels lead to oxidative stress?
Associate Professor Wallace Bridge, UNSW Sydney and Bernie Landes of Nutritional Products Consulting Group discuss glutathione depletion and oxidative stress. R...
Associate Professor Wallace Bridge, UNSW Sydney and Bernie Landes of Nutritional Products Consulting Group discuss glutathione depletion and oxidative stress. Repeated exposure to oxidative stress can result in an accumulation of permanent damage to cells and their progeny.
In many diseases and disorders, the first enzyme (glutamate cysteine ligase) involved in the synthesis of glutathione becomes dysfunctional and maintains glutathione (homeostasis) at levels too low to protect against oxidative stress.
Bernie ponders whether accumulated oxidative stress damage may actually be one of the causes of this enzyme dysfunction with Wallace commenting that the nature of how the enzyme becomes dysfunctional is the subject of ongoing research.
To know more visit us on https://www.continualg.com
https://wn.com/How_Does_Low_Glutathione_Levels_Lead_To_Oxidative_Stress
Associate Professor Wallace Bridge, UNSW Sydney and Bernie Landes of Nutritional Products Consulting Group discuss glutathione depletion and oxidative stress. Repeated exposure to oxidative stress can result in an accumulation of permanent damage to cells and their progeny.
In many diseases and disorders, the first enzyme (glutamate cysteine ligase) involved in the synthesis of glutathione becomes dysfunctional and maintains glutathione (homeostasis) at levels too low to protect against oxidative stress.
Bernie ponders whether accumulated oxidative stress damage may actually be one of the causes of this enzyme dysfunction with Wallace commenting that the nature of how the enzyme becomes dysfunctional is the subject of ongoing research.
To know more visit us on https://www.continualg.com
- published: 12 Sep 2019
- views: 19973