'+pages+''); $('.stream > div:odd').addClass('bgr_color'); updateHeight('#history'); }); window.activateTabArea = ensure(function(tab, areas){ var parsed = false; var parts = (areas || '').split('/'); window.fsonload = $.inArray('fs', parts) >= 0; if(fsonload){ parts.splice(parts.indexOf('fs'), 1); } var replayMode = false; if($.inArray('replay', parts)>=0){ replayMode = 'replay'; } var noSoundMode = false; if($.inArray('nosound', parts)>=0){ noSoundMode = 'nosound'; } if($.inArray('ns', parts)>=0){ noSoundMode = 'ns'; } var previewMode = null; if($.inArray('p', parts)>=0){ previewMode = 'p'; } if($.inArray('preview', parts)>=0){ previewMode = 'preview'; } if($.inArray('repeat', parts)>=0){ replayMode = 'repeat'; } if($.inArray('r', parts)>=0 || $.inArray('ro', parts)>=0){ replayMode = 'r'; } if(replayMode){ parts.splice(parts.indexOf(replayMode), 1); } if(noSoundMode){ parts.splice(parts.indexOf(noSoundMode), 1); } if(previewMode){ parts.splice(parts.indexOf(previewMode), 1); } if(previewMode){ if(!parts.length){ parts = ['1-14', '999:59']; } } var area = parts[0]; if(tab == 'history' && false){ var page = parseInt(area || '1') || 1; $.ajax({ url: 'https://login.wn.com/recent/json/?pp='+history_pp+'&skip='+history_pp*(page-1), dataType: 'jsonp', success: function(response){ $ensure(function(){ renderHistory(response, page); }); } }); return true; } if(tab == 'global_history' && false){ var page = parseInt(area || '1') || 1; globalHistory.fetchStream(page, '', function(){ updateHeight('#global_history'); }); return true; } if(tab == 'my_playlists' && false){ var page = parseInt(area || '1') || 1; myPlaylists.fetchStream(page, '', function(){ updateHeight('#my_playlists'); }); return true; } if(tab == 'my_videos' && false){ var page = parseInt(area || '1') || 1; myVideos.fetchStream(page, '', function(){ updateHeight('#my_videos'); }); return true; } if(tab == 'related_sites' && areas && matchPosition(areas)){ var seconds = parsePosition(areas); scrollRelated(seconds); return false; } if(matchPosition(area) || matchAction(area)){ parts.unshift('1'); area = parts[0]; } if(tab == 'expand' && area && area.match(/\d+/)) { var num = parseInt(area); if(num < 100){ //FIX ME. Load news page with ajax here } else if(num > 1900){ //FIX ME. Load timeline page with ajax here } } else if(tab.match(/^playlist\d+$/)){ var playerId = parseInt(tab.substring(8)); var vp = videoplayers[playerId]; window.descriptionsholder = $('.descriptionsplace'); if(!vp) return; // why? no player? if(replayMode){ $('.replaycurrent'+playerId).attr('checked', true); vp.setReplayCurrent(true); } var playQueue = []; window.playQueue = playQueue; var playQueuePosition = 0; var playShouldStart = null; var playShouldStop = null; var parseList = function(x){ var items = x.split(/;|,/g); var results = []; for (i in items){ try{ var action = parseAction(vp, items[i]); if(!action.video){ if(window.console && console.log) console.log("Warning: No video for queued entry: " + items[i]); }else{ results.push(action); } }catch(e){ if(window.console && console.log) console.log("Warning: Can''t parse queue entry: " + items[i]); } } return results; }; var scrollToPlaylistPosition = function(vp){ var ppos = vp.getPlaylistPosition(); var el = vp.playlistContainer.find('>li').eq(ppos); var par = el.closest('.playlist_scrollarea'); par.scrollTop(el.offset().top-par.height()/2); } var updateVolumeState = function(){ if(noSoundMode){ if(noSoundMode == 'turn-on'){ clog("Sound is on, vsid="+vp.vsid); vp.setVolumeUnMute(); noSoundMode = false; }else{ clog("Sound is off, vsid="+vp.vsid); vp.setVolumeMute(); noSoundMode = 'turn-on'; } } } var playQueueUpdate = function(){ var playPosition = playQueue[playQueuePosition]; vp.playFromPlaylist(playPosition.video); scrollToPlaylistPosition(vp); playShouldStart = playPosition.start; playShouldStop = playPosition.stop; }; var playQueueAdvancePosition = function(){ clog("Advancing play position..."); playQueuePosition ++; while(playQueuePosition < playQueue.length && !playQueue[playQueuePosition].video){ playQueuePosition ++; } if(playQueuePosition < playQueue.length){ playQueueUpdate(); }else if(vp.getReplayCurrent()){ playQueuePosition = 0; playQueueUpdate(); vp.seekTo(playShouldStart); vp.playVideo(); }else{ vp.pauseVideo(); playShouldStop = null; playShouldStart = null; } }; function loadMoreVideos(playerId, vp, start, finish, callback){ var playlistInfo = playlists[playerId-1]; if(playlistInfo.loading >= finish) return; playlistInfo.loading = finish; $.ajax({ url: '/api/upge/cheetah-photo-search/query_videos2', dataType: 'json', data: { query: playlistInfo.query, orderby: playlistInfo.orderby, start: start, count: finish-start }, success: function(response){ var pl = vp.getPlaylist().slice(0); pl.push.apply(pl, response); vp.setPlaylist(pl); callback(); } }); } if(parts.length == 1 && matchDash(parts[0])){ var pl = vp.getActualPlaylist(); var vids = parseDash(parts[0]); parts = []; for(var i = 0; i < vids.length; i++){ playQueue.push({ 'video': pl[vids[i]-1], 'start': 0, 'stop': null }) } if(vids.length){ if(vids[vids.length-1]-1>=pl.length){ loadMoreVideos(playerId, vp, pl.length, vids[vids.length-1], function(){ if(fsonload){ activateTabArea(tab, parts[0]+'/fs'); }else{ activateTabArea(tab, parts[0]); } var pls = vp.getPlaylist(); vp.playFromPlaylist(pls[pls.length-1]); vp.playVideo(); scrollToPlaylistPosition(vp); }); return true; } } if(playQueue){ playQueueUpdate(); vp.playVideo(); parsed = true; playShouldStart = 0; } } if(previewMode){ var vids = []; var dur = 0; var pl = vp.getActualPlaylist(); area = parts[0]; if(parts.length == 1 && matchPosition(parts[0])){ vids = parseDash('1-'+pl.length); dur = parsePosition(parts[0]); parts = []; }else if(parts.length == 1 && matchDash(parts[0])){ vids = parseDash(parts[0]); dur = parsePosition("999:59"); parts = []; } if(parts.length == 2 && matchDash(parts[0]) && matchPosition(parts[1])){ vids = parseDash(parts[0]); dur = parsePosition(parts[1]); parts = []; } for(var i = 0; i < vids.length; i++){ playQueue.push({ 'video': pl[vids[i]-1], 'start': 0, 'stop': dur }) } if(playQueue){ playQueueUpdate(); vp.playVideo(); parsed = true; } } if(parts.length>1){ for(var i = 0; i < parts.length; i++){ var sel = findMatchingVideo(vp, parts[i]); if(sel){ playQueue.push({ 'video': sel, 'start': 0, 'stop': null }) } } if(playQueue){ playQueueUpdate(); vp.playVideo(); parsed = true; } }else if(area){ var sel = findMatchingVideo(vp, area); if(sel){ vp.playFromPlaylist(sel); playShouldStart = 0; parsed = true; } } if(fsonload || replayMode){ playShouldStart = 0; } if(document.location.search.match('at=|queue=')){ var opts = document.location.search.replace(/^\?/,'').split(/&/g); for(var o in opts){ if(opts[o].match(/^at=(\d+:)?(\d+:)?\d+$/)){ playShouldStart = parsePosition(opts[o].substr(3)) } if(opts[o].match(/^queue=/)){ playQueue = parseList(opts[o].substr(6)); if(playQueue){ playQueuePosition = 0; playQueueUpdate(); } } } } if(matchPosition(parts[1])){ playShouldStart = parsePosition(parts[1]); parsed = true; } if(matchAction(parts[1])){ var action = parseAction(vp, area+'/'+parts[1]); playShouldStart = action.start; playShouldStop = action.stop; parsed = true; } if(playShouldStart !== null && !playQueue.length){ playQueue.push({ video: vp.getCurrentVideo(), start: playShouldStart, stop: playShouldStop }); } if(playShouldStart != null){ setInterval(function(){ if(playShouldStop && vp.currentPlayer && vp.currentPlayer.getCurrentTime() > playShouldStop){ playShouldStop = null; if(vp.getCurrentVideo() == playQueue[playQueuePosition].video){ playQueueAdvancePosition(); }else{ playShouldStart = null; } } }, 500); vp.playerContainer.bind('videoplayer.player.statechange', function(e, state){ if(state == 'ended'){ // advance to the next video playQueueAdvancePosition(); } }); vp.playerContainer.bind('videoplayer.player.readychange', function(e, state){ if(state){ updateVolumeState(); if(playShouldStart !== null){ vp.seekTo(playShouldStart); playShouldStart = null; }else{ playShouldStop = null; // someone started other video, stop playing from playQueue } } if(fsonload) { triggerFullscreen(playerId); fsonload = false; } }); } } else if(tab.match(/^wiki\d+$/)){ if(firstTimeActivate){ load_wiki($('#'+tab), function(){ if(area){ var areaNode = $('#'+area); if(areaNode.length>0){ $('html, body').scrollTop(areaNode.offset().top + 10); return true; } } }); } } return parsed; }) window.activateTab = ensure(function(tab, area){ window.activeArea = null; if(tab == 'import_videos'){ if(area){ import_videos(area); }else{ start_import(); } return true; } if(tab == 'chat'){ update_chat_position($('.chat').eq(0)); window.activeArea = 'chat'; jQuery('.tabtrigger').offscreentabs('activateTab', 'chat'); return true; } if(tab in rev_names){ tab = rev_names[tab]; } if(tab.match(':')){ return false; } var sup = $('ul li a[id=#'+tab+']'); if(sup && sup.length>0){ window.activeArea = area; sup.first().click(); if(!window.activateTabArea(tab, area)){ window.activeArea = null; } window.activeArea = null; return true; }else{ var have_tabs = $('#playlist_menu li').length; if(tab.match(/^playlists?\d+$/)){ var to_add = +tab.substring(8).replace(/^s/,'')-have_tabs; if(to_add>0 && have_tabs){ add_more_videos(to_add); return true; } } } return false; }); window.currentPath = ensure(function(){ return window.lastHistory.replace(basepath, '').split('?')[0]; }); window.main_tab = window.main_tab || 'videos'; window.addHistory = ensure(function(path){ if(window.console && console.log) console.log("Adding to history: "+path); if(window.history && history.replaceState && document.location.hostname.match(/^(youtube\.)?(\w{2,3}\.)?wn\.com$/)){ if(path == main_tab || path == main_tab+'/' || path == '' || path == '/') { path = basepath; } else if( path.match('^'+main_tab+'/') ){ path = basepath + '/' + path.replace(main_tab+'/', '').replace('--','/'); } else { path = basepath + '/' + path.replace('--','/'); } if(document.location.search){ path += document.location.search; } if(window.lastHistory) { history.pushState(null, null, path); } else if(window.lastHistory != path){ history.replaceState(null, null, path); window.lastHistory = path; } } else{ path = path.replace('--','/'); if(path == main_tab || path == main_tab+'/' || path == '' || path == '/') { path = ''; } if(window.lastHistory != '/'+path){ window.location.hash = path? '/'+path : ''; window.lastHistory = '/'+path; } } }); $('.tabtrigger li a').live('click', ensure(function() { var tab = $(this).attr('id'); if(tab.substring(0,1) == '#'){ var name = tab.substring(1); if(name in menu_names){ name = menu_names[name][0]; } realTab = rev_names[name]; $('#'+realTab).show(); if(window.console && console.log) console.log("Triggering tab: "+name+(window.activeArea?" activeArea="+window.activeArea:'')); var path = name; if(window.activeArea){ path = path + '/' + window.activeArea; } if(tab.match(/#playlist\d+/) || tab.match(/#details\d+/)){ $('.multiple-playlists').show(); $('.related_playlist').show(); $('.longest_videos_playlist').show(); }else { $('.multiple-playlists').hide(); $('.related_playlist').hide(); $('.longest_videos_playlist').hide(); } // start the related script only when the tab is on screen showing if (tab.match(/related_sites/)) { if (mc) { mc.startCredits(); } } window.activeTab = realTab; addHistory(path); setTimeout(ensure(function(){ if(tab.match(/language--/)){ $('.tabtrigger').offscreentabs('activateTab', 'language'); } if(tab.match(/weather/)) { $('.tabtrigger').offscreentabs('activateTab', 'weather'); loadContinent(); } updateMenus(tab); updateHeight(); }), 10); } return false; })); }); -->

Cell junction

A cell junction (or intercellular bridge) is a type of structure that exists within the tissue of some multicellular organisms, such as animals. Cell junctions consist of multiprotein complexes that provide contact between neighbouring cells or between a cell and the extracellular matrix. They also build up the paracellular barrier of epithelia and control the paracellular transport. Cell junctions are especially abundant in epithelial tissues.

Cell junctions are especially important in enabling communication between neighboring cells via specialized proteins called communicating junctions. Cell junctions are also important in reducing stress placed upon cells.

Types

In vertebrates, there are three major types of cell junction:

  • Adherens junctions, desmosomes and hemidesmosomes (anchoring junctions)
  • Gap junctions (communicating junction)
  • Tight junctions (occluding junctions)
  • Invertebrates have several other types of specific junctions, for example septate junctions or the C. elegans apical junction.

    Podcasts:

    • Cell Adhesion Molecules | Structure and Types

      Cell adhesion molecules (CAMs) are a subset of cell surface proteins that are involved in the binding of cells with other cells or with the extracellular matrix (ECM), in a process called cell adhesion. In essence, CAMs help cells stick to each other and to their surroundings. CAMs are crucial components in maintaining tissue structure and function. In fully developed animals, these molecules play an integral role in generating force and movement and consequently ensuring that organs are able to execute their functions normally. CAMs are typically single-pass transmembrane receptors and are composed of three conserved domains: an intracellular domain that interacts with the cytoskeleton, a transmembrane domain, and an extracellular domain. These proteins can interact in several different w...

      published: 02 Nov 2021
    • Cell Adhesion Molecules: Cadherin, Selectin, IgSF, Integrin | CELL BIOLOGY CSIR NET Lifescience

      Cell Adhesion Molecules (CAM): Cadherin, Selectin, IgSF, Integrin Cell adhesion molecules (CAMs) are a subset of cell surface proteins that are involved in the binding of cells with other cells or with the extracellular matrix (ECM), in a process called cell adhesion. In essence, CAMs help cells stick to each other and to their surroundings. CAMs are crucial components in maintaining tissue structure and function. In fully developed animals, these molecules play an integral role in generating force and movement and consequently ensuring that organs are able to execute their functions normally. CAMs are typically single-pass transmembrane receptors and are composed of three conserved domains: an intracellular domain that interacts with the cytoskeleton, a transmembrane domain, and an extrac...

      published: 11 Jul 2022
    • Cell Adhesion Molecules | CAMS | Cadherin, Integrin, IGCAMS, Selectin |

      published: 22 Aug 2020
    • Introduction to Integrins

      Integrins are complex protein compounds that play important rolls throughout the body. Learn more about them here through my 3D animation created with Maxon Cinema 4D, Redshift, and Adobe Aftereffects. As stated in the video, all footage is copyrighted to Caeley Blechschmid and Augusta University. All righty are reserved.

      published: 28 Mar 2023
    • Cell Adhesion Molecules Part 1

      In this video we discuss the four different families of cell adhesion molecules, specifically looking at the immunoglobulin superfamily of cell adhesion molecules.

      published: 13 Dec 2014
    • Cell Adhesion Molecules/ CAMs/ Integrins/ Adhesion molecules/ cadherins/selectins.

      1. Integrins, bind to various receptors 2. Adhesion Molecules, IgG superfamily of Immunoglobulins 3. Cadherins, Ca2+-dependent molecules that mediate cell-to-cell adhesion by homophilic reactions 4. Selectins, which have lectin-like domains that bind carbohydrate 5. Gap Junction & Tight Junctions

      published: 09 Feb 2019
    • 7.9 Homophilic Repulsion of Neuronal Branches

      Neurobiology Spring 2016 Project by: Alex Tolleson, Arya Dahal, Caroline Cassidy, Farjana Lisa & Gilbert Loiseau. Enjoy! Transcript below. Transcript: Hey guys. I was wondering lately: why is that axons from the same neuron don't overlap? That's easy. It's right there There are two types of branching mechanisms: The first mechanism is called growth cone splitting where a growth cones splits into two or more branches. The second mechanism is called interstitial branching where a branch extends from the trunk of the original axon or dendrite. Axonal and dendritic branches should not overlap. And this is where Down syndrome cell adhesion molecule or dscam comes in. As its name implies, dscam is a protein that helps prevent axon and dendrite branches from adhering to each other in D...

      published: 06 Apr 2016
    • Cell adhesion molecules/ Cadherins/integrins/IgSF/selectins

      This lecture is about cell adhesion molecules.Cell adhesion molecules (CAMs) are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix (ECM) in the process called cell adhesion.There are four major superfamilies or groups of CAMs: the immunoglobulin super family of cell adhesion molecules (IgCAMs), Cadherins, Integrins and selectins

      published: 05 Jun 2020
    • Cell Adhesion Molecules (CAMs)

      Structurally and functionally similar cell are grouped together to form tissues. Cell adhesion molecules play important role in formation of tissues as well as attachment of cells to the basal lamina. This video describes the various types of CAMs and their functions. Resources used Ganong's review of medical Physiology Guyton & Hall textbook of medical Physiology A concise textbook of medical Physiology Gray's anatomy Online sources Post your queries & suggestions in the comment box below or You can contact me at [email protected]

      published: 12 Mar 2022
    • Cell Physiology: Genes, Cell Adhesion Molecules

      contact us - [email protected] , +917863822668 Soft copy of my all topics notes is available and link for the app having soft copy is -https://play.google.com/store/apps/details?id=co.groot.spizl You have to download the app and subscribe the course to get notes Hard copy of my all topics notes is also available and link to purchase my notes are - https://dl.flipkart.com/s/OlCM93NNNN and Physiology Notes https://www.amazon.in/dp/9354937284/ref=cm_sw_r_awdo_2626BYD6F7TC6TR4X77Y so you can purchase physiology notes Practicable has its own app now. Keep learning, keep growing. Download now: http://on-app.in/app/home?orgCode=kyjym&referrer=utm_source=whatsapp&utm_medium=student-app-referral

      published: 26 Mar 2022
    Cell Adhesion Molecules | Structure and Types
    6:16

    Cell Adhesion Molecules | Structure and Types

    • Order:
    • Duration: 6:16
    • Uploaded Date: 02 Nov 2021
    • views: 137382
    Cell adhesion molecules (CAMs) are a subset of cell surface proteins that are involved in the binding of cells with other cells or with the extracellular matrix (ECM), in a process called cell adhesion. In essence, CAMs help cells stick to each other and to their surroundings. CAMs are crucial components in maintaining tissue structure and function. In fully developed animals, these molecules play an integral role in generating force and movement and consequently ensuring that organs are able to execute their functions normally. CAMs are typically single-pass transmembrane receptors and are composed of three conserved domains: an intracellular domain that interacts with the cytoskeleton, a transmembrane domain, and an extracellular domain. These proteins can interact in several different ways. The first method is through homophilic binding, where CAMs bind with the same CAMs. They are also capable of heterophilic binding, meaning a CAM on one cell will bind with different CAMs on another cell. There are four major superfamilies or groups of CAMs: the immunoglobulin super family of cell adhesion molecules (IgCAMs), Cadherins, Integrins, and the Superfamily of C-type of lectin-like domains proteins (CTLDs). Proteoglycans are also considered to be a class of CAMs. One classification system involves the distinction between calcium-independent CAMs and calcium-dependent CAMs.[7] Integrins and the Ig-superfamily CAMs do not depend on Ca2+ while cadherins and selectins depend on Ca2+. In addition, integrins participate in cell–matrix interactions, while other CAM families participate in cell–cell interactions. Immunoglobulin superfamily CAMs (IgSF CAMs) is regarded as the most diverse superfamily of CAMs. This family is characterized by their extracellular domains containing Ig-like domains. Integrins, one of the major classes of receptors within the ECM,mediates cell–ECM interactions with collagen, fibrinogen, fibronectin, and vitronectin. Integrins provide essential links between the extracellular environment and the intracellular signalling pathways, which can play roles in cell behaviours such as apoptosis, differentiation, survival, and transcription. The cadherins are homophilic Ca2+ -dependent glycoproteins. The classic cadherins (E-, N- and P-) are concentrated at the intermediate cell junctions, which link to the actin filament network through specific linking proteins called catenins. The selectins are a family of heterophilic CAMs that are dependent on fucosylated carbohydrates, e.g., mucins for binding. The three family members are E-selectin (endothelial), L-selectin (leukocyte), and P-selectin (platelet).
    https://wn.com/Cell_Adhesion_Molecules_|_Structure_And_Types
    Cell Adhesion Molecules: Cadherin, Selectin, IgSF, Integrin | CELL BIOLOGY CSIR NET Lifescience
    26:12

    Cell Adhesion Molecules: Cadherin, Selectin, IgSF, Integrin | CELL BIOLOGY CSIR NET Lifescience

    • Order:
    • Duration: 26:12
    • Uploaded Date: 11 Jul 2022
    • views: 9222
    Cell Adhesion Molecules (CAM): Cadherin, Selectin, IgSF, Integrin Cell adhesion molecules (CAMs) are a subset of cell surface proteins that are involved in the binding of cells with other cells or with the extracellular matrix (ECM), in a process called cell adhesion. In essence, CAMs help cells stick to each other and to their surroundings. CAMs are crucial components in maintaining tissue structure and function. In fully developed animals, these molecules play an integral role in generating force and movement and consequently ensuring that organs are able to execute their functions normally. CAMs are typically single-pass transmembrane receptors and are composed of three conserved domains: an intracellular domain that interacts with the cytoskeleton, a transmembrane domain, and an extracellular domain. These proteins can interact in several different ways. The first method is through homophilic binding, where CAMs bind with the same CAMs. They are also capable of heterophilic binding, meaning a CAM on one cell will bind with different CAMs on another cell. Immunoglobulin superfamily CAMs (IgSF CAMs) is regarded as the most diverse superfamily of CAMs. This family is characterized by their extracellular domains containing Ig-like domains. Integrins, one of the major classes of receptors within the ECM,mediates cell–ECM interactions with collagen, fibrinogen, fibronectin, and vitronectin. Integrins provide essential links between the extracellular environment and the intracellular signalling pathways, which can play roles in cell behaviours such as apoptosis, differentiation, survival, and transcription. The cadherins are homophilic Ca2+ -dependent glycoproteins. The classic cadherins (E-, N- and P-) are concentrated at the intermediate cell junctions, which link to the actin filament network through specific linking proteins called catenins. The selectins are a family of heterophilic CAMs that are dependent on fucosylated carbohydrates, e.g., mucins for binding. The three family members are E-selectin (endothelial), L-selectin (leukocyte), and P-selectin (platelet). 0:30 Cell adhesion molecules 3:00 Homophilic and Heterophilic interaction 5:06 Different types of CAMs 5:33 Cadherin 15:13 IgSF 19:21 Selectin 22: 31 Integrin ➖➖➖➖➖➖➖➖➖➖➖➖ Any doubts regarding this topic? Feel free to comment here below. ➖➖➖➖➖➖➖➖➖➖➖➖ If you like this video and find it useful Please Support me with your LIKES, SUBSCRIBE to this channel and SHARE with your friends SUBSCRIBE: https://bit.ly/34qhQVG ➖➖➖➖➖➖➖➖➖➖➖➖ Telegram channel : https://t.me/BioVidyalaya Facebook: https://www.facebook.com/BioVidyalaya ➖➖➖➖➖➖➖➖➖➖➖➖ ©NOTE : Some Images, Graphics, are shown​ in this video May be Copyrighted to respected owners. ➖➖➖➖➖➖➖➖➖➖➖➖ KEEP WATCHING... THANK YOU FOR THE SUPPORT Chithra #csirnet2022 | #BioVidyalaya | #cellbiology cell biology part b csir net, csir net cell biology, csir net cell biology topics, cell biology, cell adhesion, cell adhesion molecules, cadherin in cell adhesion, imtegrin function, selectin binding, icam, vcam, n cam, csir ugc net 2022, cell biology for jrf exam, CSIR NET Life Sciences preparation csir net life science lecture in english CSIR NET lifescience unit 2 csir net life science cell biology notes for csir net CSIR net lifescience class in english CSIR net life science free lecture videos life science lectures free CSIR net life science best youtube channel CSIR net lifescience concept Biology channel Biovidyalaya by chithra
    https://wn.com/Cell_Adhesion_Molecules_Cadherin,_Selectin,_Igsf,_Integrin_|_Cell_Biology_Csir_Net_Lifescience
    Cell Adhesion Molecules | CAMS | Cadherin, Integrin, IGCAMS, Selectin |
    3:01

    Cell Adhesion Molecules | CAMS | Cadherin, Integrin, IGCAMS, Selectin |

    • Order:
    • Duration: 3:01
    • Uploaded Date: 22 Aug 2020
    • views: 34536
    https://wn.com/Cell_Adhesion_Molecules_|_Cams_|_Cadherin,_Integrin,_Igcams,_Selectin_|
    Introduction to Integrins
    1:06

    Introduction to Integrins

    • Order:
    • Duration: 1:06
    • Uploaded Date: 28 Mar 2023
    • views: 23806
    Integrins are complex protein compounds that play important rolls throughout the body. Learn more about them here through my 3D animation created with Maxon Cinema 4D, Redshift, and Adobe Aftereffects. As stated in the video, all footage is copyrighted to Caeley Blechschmid and Augusta University. All righty are reserved.
    https://wn.com/Introduction_To_Integrins
    Cell Adhesion Molecules Part 1
    10:03

    Cell Adhesion Molecules Part 1

    • Order:
    • Duration: 10:03
    • Uploaded Date: 13 Dec 2014
    • views: 103533
    In this video we discuss the four different families of cell adhesion molecules, specifically looking at the immunoglobulin superfamily of cell adhesion molecules.
    https://wn.com/Cell_Adhesion_Molecules_Part_1
    Cell Adhesion Molecules/ CAMs/ Integrins/ Adhesion molecules/ cadherins/selectins.
    6:23

    Cell Adhesion Molecules/ CAMs/ Integrins/ Adhesion molecules/ cadherins/selectins.

    • Order:
    • Duration: 6:23
    • Uploaded Date: 09 Feb 2019
    • views: 58826
    1. Integrins, bind to various receptors 2. Adhesion Molecules, IgG superfamily of Immunoglobulins 3. Cadherins, Ca2+-dependent molecules that mediate cell-to-cell adhesion by homophilic reactions 4. Selectins, which have lectin-like domains that bind carbohydrate 5. Gap Junction & Tight Junctions
    https://wn.com/Cell_Adhesion_Molecules_Cams_Integrins_Adhesion_Molecules_Cadherins_Selectins.
    7.9 Homophilic Repulsion of Neuronal Branches
    5:01

    7.9 Homophilic Repulsion of Neuronal Branches

    • Order:
    • Duration: 5:01
    • Uploaded Date: 06 Apr 2016
    • views: 418
    Neurobiology Spring 2016 Project by: Alex Tolleson, Arya Dahal, Caroline Cassidy, Farjana Lisa & Gilbert Loiseau. Enjoy! Transcript below. Transcript: Hey guys. I was wondering lately: why is that axons from the same neuron don't overlap? That's easy. It's right there There are two types of branching mechanisms: The first mechanism is called growth cone splitting where a growth cones splits into two or more branches. The second mechanism is called interstitial branching where a branch extends from the trunk of the original axon or dendrite. Axonal and dendritic branches should not overlap. And this is where Down syndrome cell adhesion molecule or dscam comes in. As its name implies, dscam is a protein that helps prevent axon and dendrite branches from adhering to each other in Drosophila neurons. The equivalent protein in mammals is called protocadherins. This is the Dscam gene in Drosophila. It contains 4 variable exon regions shown by the red, blue, green and yellow vertical lines. Each vertical line is an exon variant and one from each region is chosen for each dscam due to alternative splicing. This allows the wide range of dscams isoforms. There are about 38000 isoforms of dscam in flies due to alternative splicing. Each neuron has a different dscam isoform. Two identical isoforms of dscam bind strongly to each other. This is called homophilic binding. Interestingly, strong binding leads to strong repulsion between the two isoforms!!!! Causing the two branches to extend in different directions. Because each neuron has the same dscam isoform, the branches do not stick together. The self-avoidance repulsion mechanism is still yet not fully understood. Two different isoforms of dscam do not bind strongly to each other and therefore, will not cause strong repulsion. In a wild type neuron, the extensions move away from each other and don’t overlap because they have identical dscam isoforms. In this representation, the scissors are identical isoforms of dscam and the string is a neuronal extension. When scissors are present, they prevent neuronal extension overlap and allow branching as shown. In a neuron with dscam deletion, the extensions don’t repel each other and stick together. Similarly in this representation, due to the lack of scissors or dscam, the strings stay attached. Protocadherins have a similar role to dscams in mammals. They are calcium-dependent cell adhesion proteins that are important in cell binding and recognition. There are twenty different cadherin genes and more for protocadherins which leads to 58 extracellular domain variations. Similar to dscam knockout studies, protocadherin knockout also results in clumping of dendrites from the same cell. Dscams and protocadherins are also important in dendritic tiling. This refers to the process by which neuronal extensions of the same type avoid each other. In axonal or dendritic branching, dscam proteins in Drosophila and protocadherins in mammals use homophilic binding based on isoforms to ensure self-avoidance in extensions from the same neuron. Our take home message is: Opposites attract, likes repel.
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    Cell adhesion molecules/ Cadherins/integrins/IgSF/selectins
    9:20

    Cell adhesion molecules/ Cadherins/integrins/IgSF/selectins

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    • Uploaded Date: 05 Jun 2020
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    This lecture is about cell adhesion molecules.Cell adhesion molecules (CAMs) are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix (ECM) in the process called cell adhesion.There are four major superfamilies or groups of CAMs: the immunoglobulin super family of cell adhesion molecules (IgCAMs), Cadherins, Integrins and selectins
    https://wn.com/Cell_Adhesion_Molecules_Cadherins_Integrins_Igsf_Selectins
    Cell Adhesion Molecules (CAMs)
    14:40

    Cell Adhesion Molecules (CAMs)

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    • Uploaded Date: 12 Mar 2022
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    Structurally and functionally similar cell are grouped together to form tissues. Cell adhesion molecules play important role in formation of tissues as well as attachment of cells to the basal lamina. This video describes the various types of CAMs and their functions. Resources used Ganong's review of medical Physiology Guyton & Hall textbook of medical Physiology A concise textbook of medical Physiology Gray's anatomy Online sources Post your queries & suggestions in the comment box below or You can contact me at [email protected]
    https://wn.com/Cell_Adhesion_Molecules_(Cams)
    Cell Physiology: Genes, Cell Adhesion Molecules
    33:55

    Cell Physiology: Genes, Cell Adhesion Molecules

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    • Duration: 33:55
    • Uploaded Date: 26 Mar 2022
    • views: 201
    contact us - [email protected] , +917863822668 Soft copy of my all topics notes is available and link for the app having soft copy is -https://play.google.com/store/apps/details?id=co.groot.spizl You have to download the app and subscribe the course to get notes Hard copy of my all topics notes is also available and link to purchase my notes are - https://dl.flipkart.com/s/OlCM93NNNN and Physiology Notes https://www.amazon.in/dp/9354937284/ref=cm_sw_r_awdo_2626BYD6F7TC6TR4X77Y so you can purchase physiology notes Practicable has its own app now. Keep learning, keep growing. Download now: http://on-app.in/app/home?orgCode=kyjym&referrer=utm_source=whatsapp&utm_medium=student-app-referral
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    Cell Adhesion Molecules | Structure and Types

    Cell adhesion molecules (CAMs) are a subset of cell surface proteins that are involved in the binding of cells with other cells or with the extracellular matrix (ECM), in a process called cell adhesion. In essence, CAMs help cells stick to each other and to their surroundings. CAMs are crucial components in maintaining tissue structure and function. In fully developed animals, these molecules play an integral role in generating force and movement and consequently ensuring that organs are able to execute their functions normally. CAMs are typically single-pass transmembrane receptors and are composed of three conserved domains: an intracellular domain that interacts with the cytoskeleton, a transmembrane domain, and an extracellular domain. These proteins can interact in several different ways. The first method is through homophilic binding, where CAMs bind with the same CAMs. They are also capable of heterophilic binding, meaning a CAM on one cell will bind with different CAMs on another cell. There are four major superfamilies or groups of CAMs: the immunoglobulin super family of cell adhesion molecules (IgCAMs), Cadherins, Integrins, and the Superfamily of C-type of lectin-like domains proteins (CTLDs). Proteoglycans are also considered to be a class of CAMs. One classification system involves the distinction between calcium-independent CAMs and calcium-dependent CAMs.[7] Integrins and the Ig-superfamily CAMs do not depend on Ca2+ while cadherins and selectins depend on Ca2+. In addition, integrins participate in cell–matrix interactions, while other CAM families participate in cell–cell interactions. Immunoglobulin superfamily CAMs (IgSF CAMs) is regarded as the most diverse superfamily of CAMs. This family is characterized by their extracellular domains containing Ig-like domains. Integrins, one of the major classes of receptors within the ECM,mediates cell–ECM interactions with collagen, fibrinogen, fibronectin, and vitronectin. Integrins provide essential links between the extracellular environment and the intracellular signalling pathways, which can play roles in cell behaviours such as apoptosis, differentiation, survival, and transcription. The cadherins are homophilic Ca2+ -dependent glycoproteins. The classic cadherins (E-, N- and P-) are concentrated at the intermediate cell junctions, which link to the actin filament network through specific linking proteins called catenins. The selectins are a family of heterophilic CAMs that are dependent on fucosylated carbohydrates, e.g., mucins for binding. The three family members are E-selectin (endothelial), L-selectin (leukocyte), and P-selectin (platelet).
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    Cell junction

    A cell junction (or intercellular bridge) is a type of structure that exists within the tissue of some multicellular organisms, such as animals. Cell junctions consist of multiprotein complexes that provide contact between neighbouring cells or between a cell and the extracellular matrix. They also build up the paracellular barrier of epithelia and control the paracellular transport. Cell junctions are especially abundant in epithelial tissues.

    Cell junctions are especially important in enabling communication between neighboring cells via specialized proteins called communicating junctions. Cell junctions are also important in reducing stress placed upon cells.

    Types

    In vertebrates, there are three major types of cell junction:

  • Adherens junctions, desmosomes and hemidesmosomes (anchoring junctions)
  • Gap junctions (communicating junction)
  • Tight junctions (occluding junctions)
  • Invertebrates have several other types of specific junctions, for example septate junctions or the C. elegans apical junction.

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