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. 1996 Jan;33(1):77-9.
doi: 10.1136/jmg.33.1.77.

Evidence for a fourth locus in Usher syndrome type I

S Gerber  1 , D Larget-Piet, J M Rozet, D Bonneau, M Mathieu, V Der Kaloustian, A Munnich, J Kaplan
Affiliations

Evidence for a fourth locus in Usher syndrome type I

S Gerber et al. J Med Genet. 1996 Jan.

Abstract

Usher syndrome type I (US1) is an autosomal recessive condition in which three different genes have been already localised (USH1A, USH1B, and USH1C on chromosomes 14q32, 11q13, and 11p15 respectively). The genetic heterogeneity of US1 has been confirmed in a previous study by linkage analysis of 20 French pedigrees. Here, we report the genetic exclusion of the three previously reported loci in two large multiplex families of Moroccan and Pakistani origin, suggesting the existence of at least a fourth locus in Usher syndrome type I.

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References

    1. Genomics. 1990 Jun;7(2):245-9 - PubMed
    1. Genomics. 1992 Dec;14(4):979-87 - PubMed
    1. Genomics. 1992 Dec;14(4):988-94 - PubMed
    1. Genomics. 1992 Dec;14(4):995-1002 - PubMed
    1. J Med Genet. 1993 Oct;30(10):843-8 - PubMed

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