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Randomized Controlled Trial
. 2024 Dec;21(1):2393364.
doi: 10.1080/15502783.2024.2393364. Epub 2024 Aug 20.

Rehydration effect of qingshu buye decoction on exercise and high temperature-induced dehydration

Huanyu Jiang  1 , Jiankun Gao  2 , Huan Wang  3 , Lin Zhao  4 , Yingduo Yang  5 , Jiahua Ma  6   7 , Shan Gu  8 , Fenglin Hu  8 , Quanyu Du  9 , Fei Wang  4
Affiliations
Randomized Controlled Trial

Rehydration effect of qingshu buye decoction on exercise and high temperature-induced dehydration

Huanyu Jiang et al. J Int Soc Sports Nutr. 2024 Dec.

Abstract

Objective: The aim of this study was to conduct a comprehensive evaluation of the rehydration efficacy of QSBYD and elucidate its potential underlying mechanism.

Design: 38 participants were randomly assigned to receive either QSBYD or placebo before and after exercise and heat-induced dehydration. Hydration indicators were measured over time. Blood tests assessed cellular anaerobic respiration metabolites, serum inflammatory markers, and coagulation markers. Perceptual measures of thirst, fatigue, and muscular soreness were also taken.

Results: QSBYD consumption resulted in lower urine volume (Control vs. QSBYD: 260.83 ± 167.99 ml vs. 187.78 ± 141.34 ml) and smaller decrease in percentage of nude body weight change from baseline (Control vs. QSBYD: -0.52 ± 0.89% vs. -0.07 ± 0.52%). Although no significant differences in urine specific gravity, QSBYD resulted in reduced urine volume at 120 min, suggesting improved fluid retention. Furthermore, QSBYD resulted in lower levels of IL-1β (Control vs. QSBYD: 2.40 ± 0.68 vs. 1.33 ± 0.66 pg/mL), suggesting QSBYD may provide benefits beyond hydration.

Conclusion: Further investigation into the underlying mechanisms and long-term effects of QSBYD on hydration is warranted. QSBYD may be an effective alternative to commercial sports drinks in mitigating dehydration effects.

Keywords: Qingshu buye decoction; dehydration; exercise; high temperature; hydration.

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Conflict of interest statement

No potential conflict of interest was reported by the author(s).

Figures

Figure 1.
Figure 1.
The measured indicators and their time points in this experiment.
Figure 2.
Figure 2.
Enrollment and randomization in the overall population.
Figure 3.
Figure 3.
Measurements of dehydration status at baseline, immediate post dehydration, and after ingestion of control or QSBYD.
Figure 4.
Figure 4.
Measurements of dehydration related serum markers at baseline and after ingestion of control or QSBYD.
Figure 5.
Figure 5.
Measurements of thirst, fatigue, and muscular soreness at baseline, immediately post dehydration, 30 min, 120 min, and 24 h post dehydration.
See this image and copyright information in PMC

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References

    1. Monthly Global Climate Report for December 2021 . Asheville (NC): NOAA National Centers for Environmental Information; 2022. Jan [cited 2023 Apr 20]. [about 2 screens] [Internet]. https://www.ncei.noaa.gov/access/monitoring/monthly-report/global/202200
    1. Abbass K, Qasim MZ, Song H, et al. A review of the global climate change impacts, adaptation, and sustainable mitigation measures. Environ Sci Pollut Res. 2022;29(28):42539–16. doi: 10.1007/s11356-022-19718-6 - DOI - PMC - PubMed
    1. Adan A. Cognitive performance and dehydration. J Am Coll Nutr. 2012;31(2):71–78. doi: 10.1080/07315724.2012.10720011 - DOI - PubMed
    1. Pross N, Demazières A, Girard N, et al. Influence of progressive fluid restriction on mood and physiological markers of dehydration in women. Br J Nutr. 2013;109(2):313–321. doi: 10.1017/S0007114512001080 - DOI - PMC - PubMed
    1. Rangan GK, Dorani N, Zhang MM, et al. Clinical characteristics and outcomes of hyponatraemia associated with oral water intake in adults: a systematic review. BMJ Open. 2021;11(12):e046539. doi: 10.1136/bmjopen-2020-046539 - DOI - PMC - PubMed

Publication types

Grants and funding

This study was supported by the Sichuan Provincial Administration of Traditional Chinese Medicine under the 2022 Special Project for Innovation Teams in Science and Technology in Traditional Chinese Medicine [No. 2022C002].