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Review
. 2023 Sep 6;15(18):3876.
doi: 10.3390/nu15183876.

Metabolic Disorders and Psoriasis: Exploring the Role of Nutritional Interventions

Marco Cintoni  1   2 , Marta Palombaro  1 , Fabio Stefano Maramao  3 , Pauline Raoul  1 , Gabriele Egidi  1 , Elena Leonardi  1 , Luca Bianchi  3 , Elena Campione  3 , Emanuele Rinninella  1   2   4 , Antonio Gasbarrini  4   5 , Maria Cristina Mele  1   2   4
Affiliations
Review

Metabolic Disorders and Psoriasis: Exploring the Role of Nutritional Interventions

Marco Cintoni et al. Nutrients. .

Abstract

(1) Background: Psoriasis is a chronic autoimmune disease with a close relationship with metabolic diseases such as obesity, diabetes, and dyslipidemia. The aim of this review was to identify the relationship between psoriasis, metabolic diseases, and dietetic therapies. According to recent findings, there is a strong association between psoriasis and obesity as well as vitamin D and micronutrient deficiencies. (2) Methods: This review was conducted via PubMed, aiming to search for studies involving psoriasis linked with metabolic disorders or with nutritional treatments. (3) Results: Our review shows that a healthy lifestyle can positively influence the course of the disease. The maintaining of a proper body weight together with physical activity and good nutritional choices are associated with an improvement in psoriasis severity. A Mediterranean diet rich in fiber, vitamins, and polyphenols may indeed be a strategy for controlling psoriasis symptoms. The effectiveness of this diet lies not only in its anti-inflammatory power, but also in its ability to favorably influence the intestinal microbiota and counteract dysbiosis, which is a risk factor for many autoimmune diseases. (4) Conclusions: In synergy with standard therapy, the adoption of an appropriate diet can be recommended to improve the clinical expression of psoriasis and reduce the incidence of comorbidities.

Keywords: clinical nutrition; nutritional issues; nutritional supplementation; obesity; psoriasis.

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Conflict of interest statement

The authors declare no conflict of interest.

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This research received no external funding.