Nanomedicine and Periodontal Regenerative Treatment
- PMID: 34794551
- DOI: 10.1016/j.cden.2021.06.005
Nanomedicine and Periodontal Regenerative Treatment
Abstract
Current periodontal treatments aim to control bacterial infection and decrease inflammation. To optimize contemporary conventional treatments that present limitations owing to an inability to reach the lesion site, new methods are based on nanomedicine. Nanomedecine allows delivery of host-modulatory drugs or antibacterial molecules at the lesion site in an optimal concentration with decreased toxicity and risk of systemic side effects. Chitosan and polylactic-co-glycolic acid-loaded nanoparticles, carbon quantum dots, and mesoporous silicates open new perspectives in periodontitis management. The potential therapeutic impact of the main nanocarriers is discussed.
Keywords: Biomaterials; Inflammation; Nanocarriers; Nanomedicine; Periodontitis.
Copyright © 2021 Elsevier Inc. All rights reserved.
Similar articles
-
Multifunctional nanocarriers for the treatment of periodontitis: Immunomodulatory, antimicrobial, and regenerative strategies.Oral Dis. 2019 Nov;25(8):1866-1878. doi: 10.1111/odi.13023. Epub 2019 Jan 10. Oral Dis. 2019. PMID: 30565778 Review.
-
Controlled-release of tetracycline and lovastatin by poly(D,L-lactide-co-glycolide acid)-chitosan nanoparticles enhances periodontal regeneration in dogs.Int J Nanomedicine. 2016 Jan 18;11:285-97. doi: 10.2147/IJN.S94270. eCollection 2016. Int J Nanomedicine. 2016. PMID: 26848264 Free PMC article.
-
Potential of chitosan-based carrier for periodontal drug delivery.Colloids Surf B Biointerfaces. 2019 Jun 1;178:185-198. doi: 10.1016/j.colsurfb.2019.02.044. Epub 2019 Feb 23. Colloids Surf B Biointerfaces. 2019. PMID: 30856588 Review.
-
Regenerative potential and anti-bacterial activity of tetracycline loaded apatitic nanocarriers for the treatment of periodontitis.Biomed Mater. 2014 Jun;9(3):035002. doi: 10.1088/1748-6041/9/3/035002. Epub 2014 Mar 31. Biomed Mater. 2014. PMID: 24687419
-
Mesoporous Hydroxyapatite/Chitosan Loaded With Recombinant-Human Amelogenin Could Enhance Antibacterial Effect and Promote Periodontal Regeneration.Front Cell Infect Microbiol. 2020 Apr 29;10:180. doi: 10.3389/fcimb.2020.00180. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 32411618 Free PMC article.
Cited by
-
Guided Tissue and Bone Regeneration Membranes: A Review of Biomaterials and Techniques for Periodontal Treatments.Polymers (Basel). 2023 Aug 10;15(16):3355. doi: 10.3390/polym15163355. Polymers (Basel). 2023. PMID: 37631412 Free PMC article. Review.
-
Amelogenin-Derived Peptide (ADP-5) Hydrogel for Periodontal Regeneration: An In Vitro Study on Periodontal Cells Cytocompatibility, Remineralization and Inflammatory Profile.J Funct Biomater. 2023 Jan 18;14(2):53. doi: 10.3390/jfb14020053. J Funct Biomater. 2023. PMID: 36826852 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources