Vaccinations and secondary immune thrombocytopenia with antiphospholipid antibodies by human papillomavirus vaccine
- PMID: 27312165
- DOI: 10.1053/j.seminhematol.2016.04.014
Vaccinations and secondary immune thrombocytopenia with antiphospholipid antibodies by human papillomavirus vaccine
Abstract
A 13-year-old girl developed immune thrombocytopenic purpura (ITP) and concomitant positive antiphospholipid antibodies (aPL) following vaccination with a quadrivalent human papillomavirus (HPV) vaccine. During the course of a disease, she developed clinical manifestation with bleeding and she was treated with intravenous immunoglobulins. Consequently, the number of her platelets remained critically low and she was put on corticosteroids and rituximab. Since then, her platelet count remain within the normal range, but her aPL are still present.
Keywords: ASIA syndrome; Antiphospholipid antibodies; Human papillomavirus; Immune thrombocytopenic purpura; Molecular mimicry; Vaccine.
Published by Elsevier Inc.
Similar articles
-
Multifocal avascular necrosis in a patient with refractory immune thrombocytopenia and antiphospholipid antibodies; case report and review of literature.Platelets. 2019;30(5):664-671. doi: 10.1080/09537104.2018.1535701. Epub 2018 Oct 29. Platelets. 2019. PMID: 30373491 Review.
-
Antiphospholipids antibodies in a 12-month-old presenting with idiopathic thrombocytopenic purpura.Pediatr Hematol Oncol. 2008 Apr-May;25(3):233-5. doi: 10.1080/08880010701884733. Pediatr Hematol Oncol. 2008. PMID: 18432507
-
Successful use of rituximab in refractory idiopathic thrombocytopenic purpura in a patient with common variable immunodeficiency.J Investig Allergol Clin Immunol. 2010;20(3):259-62. J Investig Allergol Clin Immunol. 2010. PMID: 20635793
-
Incidence of Antiphospholipid Antibodies in Patients With Immune Thrombocytopenia and Correlation With Treatment With Steroids in North Indian Population.Clin Appl Thromb Hemost. 2017 Sep;23(6):657-662. doi: 10.1177/1076029616643820. Epub 2016 Apr 10. Clin Appl Thromb Hemost. 2017. PMID: 27067744
-
The hematologic manifestations of the antiphospholipid syndrome.Blood Rev. 2008 Jul;22(4):187-94. doi: 10.1016/j.blre.2008.03.005. Epub 2008 Apr 15. Blood Rev. 2008. PMID: 18417261 Review.
Cited by
-
Evaluation of patients with antiphospholipid syndrome subsequently COVID-19 vaccinations: A retrospective cohort study.Int J Rheum Dis. 2023 Feb;26(2):292-297. doi: 10.1111/1756-185X.14490. Epub 2022 Nov 12. Int J Rheum Dis. 2023. PMID: 36371485 Free PMC article.
-
COVID-19 Vaccination and the Rate of Immune and Autoimmune Adverse Events Following Immunization: Insights From a Narrative Literature Review.Front Immunol. 2022 Jul 5;13:872683. doi: 10.3389/fimmu.2022.872683. eCollection 2022. Front Immunol. 2022. PMID: 35865539 Free PMC article. Review.
-
Antiphospholipid antibodies and risk of post-COVID-19 vaccination thrombophilia: The straw that breaks the camel's back?Cytokine Growth Factor Rev. 2021 Aug;60:52-60. doi: 10.1016/j.cytogfr.2021.05.001. Epub 2021 May 28. Cytokine Growth Factor Rev. 2021. PMID: 34090785 Free PMC article. Review.
-
Idiopathic thrombocytopenic purpura treatment in a relapsed/refractory multiple myeloma patient after chimeric antigen receptor T cell therapy.Regen Ther. 2020 May 15;14:271-274. doi: 10.1016/j.reth.2020.03.005. eCollection 2020 Jun. Regen Ther. 2020. PMID: 32455157 Free PMC article.
-
Pediatric APS: State of the Art.Curr Rheumatol Rep. 2020 Mar 3;22(3):9. doi: 10.1007/s11926-020-0887-9. Curr Rheumatol Rep. 2020. PMID: 32124078
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources