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Review
. 2014 Aug;71(2):350-8.
doi: 10.1016/j.jaad.2014.03.017. Epub 2014 Apr 26.

Diet and psoriasis, part II: celiac disease and role of a gluten-free diet

Bhavnit K Bhatia  1 , Jillian W Millsop  2 , Maya Debbaneh  3 , John Koo  4 , Eleni Linos  4 , Wilson Liao  5
Affiliations
Review

Diet and psoriasis, part II: celiac disease and role of a gluten-free diet

Bhavnit K Bhatia et al. J Am Acad Dermatol. 2014 Aug.

Abstract

Patients with psoriasis have been shown to have a higher prevalence of other autoimmune diseases including celiac disease, a condition marked by sensitivity to dietary gluten. A number of studies suggest that psoriasis and celiac disease share common genetic and inflammatory pathways. Here we review the epidemiologic association between psoriasis and celiac disease and perform a meta-analysis to determine whether patients with psoriasis more frequently harbor serologic markers of celiac disease. We also examine whether a gluten-free diet can improve psoriatic skin disease.

Keywords: antigliadin; celiac disease; celiac sprue; diet; gluten-free; nutrition; psoriasis.

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Conflict of interest statement

Conflict of Interest: Dr. John Koo is a speaker for AbbVie and Leo. Dr. Koo conducts research for Amgen, Janssen, Novartis, Photomedex, Galderma, Pfizer, and Merck. Dr. Koo has no stocks, employment, or board memberships with any pharmaceutical company. None of the grants were directly related to this study. No other authors have conflicts of interest to report.

Figures

Figure 1
Figure 1
Forest plot comparing odds ratio of testing positive for celiac IgA antigliadin antibodies in psoriasis patients versus controls.
Figure 2
Figure 2
Forest plot comparing the standardized mean difference of celiac IgA antigliadin antibody levels in psoriasis patients versus controls.
See this image and copyright information in PMC

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