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. 1988 Apr;38(4):650-2.
doi: 10.1212/wnl.38.4.650.

Treatment of essential tremor with arotinolol

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Treatment of essential tremor with arotinolol

Y Kuroda et al. Neurology. 1988 Apr.

Abstract

We investigated the effect of arotinolol, a new peripherally acting beta-adrenergic blocker, in 15 patients with essential tremor. The patients received 30 mg per day of arotinolol for 8 weeks. Accelerometer readings showed a significant reduction in amplitude of postural tremor after treatment. Action tremor also improved to essentially the same degree as postural tremor. The present findings support the view that the therapeutic effect of beta-blockers in essential tremor is mediated by peripheral beta-adrenergic receptors.

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