Major depression in patients with borderline personality disorder: a clinical investigation
- PMID: 15898463
- DOI: 10.1177/070674370505000407
Major depression in patients with borderline personality disorder: a clinical investigation
Abstract
Objective: Borderline personality disorder (BPD) is characterized by a high frequency of comorbidity with major depressive disorder (MDD). This study aimed to compare the clinical characteristics of 2 groups of patients with MDD: those with concomitant BPD and those with other concomitant personality disorders.
Methods: We assessed 119 outpatients, using a semistructured interview for demographic and clinical features, the Structured Clinical Interview for DSM-IV, Hamilton anxiety and depression scales, the Zung Self-Rating Depression Scale (ZSDS), the Social and Occupational Functioning Assessment Scale (SOFAS), the Sheehan Disability Scale, and the Revised Childhood Experiences Questionnaire. We performed a regression analysis, using the number of criteria for BPD as the dependent variable.
Results: Severity of BPD was positively related to the ZSDS score, to self-mutilating behaviours, and to the occurrence of mood disorders in first-degree relatives; it was negatively related to the SOFAS score and age at onset of MDD.
Conclusions: Patients with comorbid MDD and BPD present differential characteristics that indicate a more serious and impairing condition with a stronger familial link with mood disorders than is shown by depression patients with other Axis II codiagnoses.
Similar articles
-
Distinguishing bipolar II depression from major depressive disorder with comorbid borderline personality disorder: demographic, clinical, and family history differences.J Clin Psychiatry. 2013 Sep;74(9):880-6. doi: 10.4088/JCP.13m08428. J Clin Psychiatry. 2013. PMID: 24107761
-
Heightened subjective experience of depression in borderline personality disorder.J Pers Disord. 2006 Aug;20(4):307-18. doi: 10.1521/pedi.2006.20.4.307. J Pers Disord. 2006. PMID: 16901256
-
[Personality disorders in a nonclinical sample of adolescents].Encephale. 2002 Nov-Dec;28(6 Pt 1):520-4. Encephale. 2002. PMID: 12506264 French.
-
Borderline personality disorder: Prevalence and psychiatric comorbidity among male offenders on probation in Sweden.Compr Psychiatry. 2015 Oct;62:63-70. doi: 10.1016/j.comppsych.2015.06.014. Epub 2015 Jun 26. Compr Psychiatry. 2015. PMID: 26343468 Review.
-
Depressive experiences in inpatients with borderline personality disorder.Psychiatr Q. 2007 Jun;78(2):129-43. doi: 10.1007/s11126-006-9033-8. Psychiatr Q. 2007. PMID: 17347875 Review.
Cited by
-
Depression with comorbid borderline personality disorder - could ketamine be a treatment catalyst?Front Psychiatry. 2024 Apr 29;15:1398859. doi: 10.3389/fpsyt.2024.1398859. eCollection 2024. Front Psychiatry. 2024. PMID: 38742125 Free PMC article. Review.
-
Risk factors for suicidal attempts in a sample of outpatients with treatment-resistant depression: an observational study.Front Psychiatry. 2024 Mar 22;15:1371139. doi: 10.3389/fpsyt.2024.1371139. eCollection 2024. Front Psychiatry. 2024. PMID: 38585482 Free PMC article.
-
Prospective Mental Images: A Transdiagnostic Approach to Negative Affectivity and Mood Dysregulation among Borderline Personality Disorder and Depression.Behav Sci (Basel). 2024 Jan 23;14(2):81. doi: 10.3390/bs14020081. Behav Sci (Basel). 2024. PMID: 38392434 Free PMC article.
-
Psychiatric Disorder in a Patient With Beckwith-Wiedemann Syndrome: A Case Report.Cureus. 2023 Jun 13;15(6):e40377. doi: 10.7759/cureus.40377. eCollection 2023 Jun. Cureus. 2023. PMID: 37456504 Free PMC article.
-
Aggression, Impulsivity and Suicidal Behavior in Depressive Disorders: A Comparison Study between New York City (US), Madrid (Spain) and Florence (Italy).J Clin Med. 2021 Jul 9;10(14):3057. doi: 10.3390/jcm10143057. J Clin Med. 2021. PMID: 34300222 Free PMC article.
MeSH terms
LinkOut - more resources
Full Text Sources
