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. 2003 Jan;160(1):178-80.
doi: 10.1176/appi.ajp.160.1.178.

Validity of the mood disorder questionnaire: a general population study

Robert M A Hirschfeld  1 , Charles Holzer, Joseph R Calabrese, Myrna Weissman, Michael Reed, Marilyn Davies, Mark A Frye, Paul Keck, Susan McElroy, Lydia Lewis, Jonathan Tierce, Karen D Wagner, Elizabeth Hazard
Affiliations

Validity of the mood disorder questionnaire: a general population study

Robert M A Hirschfeld et al. Am J Psychiatry. 2003 Jan.

Abstract

Objective: This study tested the validity in the adult general population of the Mood Disorder Questionnaire, a screening instrument for bipolar I and II disorders. The Mood Disorder Questionnaire has been validated in a psychiatric outpatient study group.

Method: A total of 711 subjects (stratified by Mood Disorder Questionnaire score) were randomly selected from a group of 85,358 adult respondents in a nationwide epidemiological general population sample that was balanced for key demographic variables. Of these, 695 subjects received a telephone interview involving an abbreviated version of the Structured Clinical Interview for DSM-IV.

Results: A sensitivity of 0.281 and a specificity of 0.972 were obtained for the Mood Disorder Questionnaire.

Conclusions: The Mood Disorder Questionnaire is a useful screening instrument for bipolar I and II disorders in the community. The operating characteristics of the Mood Disorder Questionnaire in the general population differ substantially from its characteristics in outpatient psychiatric settings.

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