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SGLT2

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SGLT2 est abbreviatura proteini 2 transportationis natrii glucosique. Functio SGLT2 in renibus reabsorptio glucosi est. Genum SGLT2 humani vocatur SLC5A2. Inhibitores SGLT2 (gliflozini) ad diabetem mellitum typi 2 tractandum praescribuntur.

Medicamenti inhibitores SGLT2 nominatur gliflozini.

Natura genetica

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Genum SGLT2 humani vocatur SLC5A2 et in chromosomate 16 humano (p11.2) invenitur[1]. Geni mutationes cum glucosuria renale familiari (abbreviatura internationalis: FRG) sociatae sint[2].

Notae

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  1. ↑ Wells RG, Mohandas TK, Hediger MA (Sep 1993). "Localization of the Na+/glucose cotransporter gene SGLT2 to human chromosome 16 close to the centromere". Genomics 17 (3): 787–9 
  2. ↑ Calado J, Loeffler J, Sakallioglu O, Gok F, Lhotta K, Barata J, Rueff J (Mar 2006). "Familial renal glucosuria: SLC5A2 mutation analysis and evidence of salt-wasting". Kidney International 69 (5): 852–5 

Nexus interni

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