Mutation Research-genetic Toxicology and Environmental Mutagenesis, 1998
. Miral 500 CS CASa 42509-80-8 , an organophosphorus insecticide, has been widely used in Colombi... more . Miral 500 CS CASa 42509-80-8 , an organophosphorus insecticide, has been widely used in Colombia to fumigate coffee plantations. Therefore, there is extensive human exposure to this pesticide. Miral's mutagenic and genotoxic activities, however, are not known. In this study, such activities of the pesticide were evaluated using the Salmonella TA98rS9 test and the chromosome aberration assay in bone marrow cells of Swiss albino CD1 male mice. All doses tested Ž . with Salmonella in the presence of S9 mix 3.2, 16, 80, 400 and 2000 mgrplate induced a mutagenic response that was three times the spontaneous mutation frequency. The mutagenic response without S9 was twice the spontaneous frequency.
Mutation Research-genetic Toxicology and Environmental Mutagenesis, 1998
. Miral 500 CS CASa 42509-80-8 , an organophosphorus insecticide, has been widely used in Colombi... more . Miral 500 CS CASa 42509-80-8 , an organophosphorus insecticide, has been widely used in Colombia to fumigate coffee plantations. Therefore, there is extensive human exposure to this pesticide. Miral's mutagenic and genotoxic activities, however, are not known. In this study, such activities of the pesticide were evaluated using the Salmonella TA98rS9 test and the chromosome aberration assay in bone marrow cells of Swiss albino CD1 male mice. All doses tested Ž . with Salmonella in the presence of S9 mix 3.2, 16, 80, 400 and 2000 mgrplate induced a mutagenic response that was three times the spontaneous mutation frequency. The mutagenic response without S9 was twice the spontaneous frequency.
Uploads
Papers by Alonso Mirales