International Collaborative for Drug Stability Testing
A BSAC initiative
Resources
Open access publications and stability testing data can be accessed below:
Drug Stability Temocillin OPAT Elastomeric devices Continuous infusion United Kingdom
PUBLISHED MANUSCRIPT: Evaluation of the stability of temocillin in elastomeric infusion devices used for outpatient parenteral antimicrobial therapy in accordance with the requirements of the UK NHS Yellow Cover Document.
European Journal of Hospital Pharmacy online (http://dx.doi.org/10.1136/ejhpharm-2022-003286)
Drug Stability ceftolozane/tazobactam OPAT Elastomeric devices continous infusion United Kingdom
PUBLISHED MANUSCRIPT: Assessment of ceftolozane/tazobactam stability in elastomeric devices and suitability for continuous infusion via outpatient parenteral antimicrobial therapy.
JAC-Antimicrobial Resistance, Volume 3, Issue 3, September 2021, dlab141
OPAT Drug stability Elastomeric devices piperacillin/tazobactam continuous infusion United Kingdom
PUBLISHED MANUSCRIPT: Assessment of the stability of citrate-buffered piperacillin/tazobactam for continuous infusion when stored in two commercially available elastomeric devices for outpatient parenteral antimicrobial chemotherapy: a study compliant with the NHS Yellow Cover Document requirements.
European Journal of Hospital Pharmacy online (http:// dx. doi. org/ 10. 1136/ ejhpharm- 2020- 002340)
Investigation Compliance Outpatient Influence Stability Meropenem United Kingdom
PUBLISHED MANUSCRIPT: Investigation of meropenem stability after reconstitution: the influence of buffering and challenges to meet the NHS Yellow Cover Document compliance for continuous infusions in an outpatient setting
European Journal of Hospital online (http: 2018;0:1–5. doi:10.1136/ejhpharm-2018-001699)
Stability Flucloxacillin United Kingdom
PUBLISHED MANUSCRIPT: Assessment of the stability of citrate-buffered flucloxacillin for injection when stored in two commercially available ambulatory elastomeric devices: INfusor LV (Baxter) and Accufuser (Woo Young Medical): a study compliant with the NHS Yellow Cover Document (YCD) requirements.
European Journal of Hospital online (http: 2018. 0:1–5. doi:10.1136/ejhpharm-2018-001515)
Stability Antimicrobial United Kingdom
PUBLISHED MANUSCRIPT: Extended stability of antimicrobial agents in administration devices
OPAT Drug stability Continuous infusion Aciclovir United Kingdom
POSTER: Aciclovir
Title: Evaluation of the stability of aciclovir in elastomeric infusion devices used for outpatient parenteral antimicrobial therapy (OPAT) services in accordance with the requirements of the UK NHS Yellow Cover Document
United Kingdom
POSTER: Amoxicillin
Scoping the stability of amoxicillin for use in Outpatient Parenteral Antimicrobial Therapy (OPAT) services in accordance with the requirements of the UK NHS Yellow Cover Document.
United Kingdom
POSTER: Ceftolozane/tazobactam
Title: Assessing the stability of ceftolozane/tazobactam (ZERBAXA®) at 5 mg/mL and 20 mg/mL following reconstitution and dilution in 0.9% saline in two commercially available elastomeric devices. Presented at the BSAC OPAT Conference, 11 December 2019.
United Kingdom
POSTER: Piperacillin/tazobactam
Title: Assessing the stability of piperacillin/tazobactam at 25 mg/mL and 90 mg/mL reconstituted and diluted in 0.3% w/v citrate buffered saline in two commercially available elastomeric devices. Presented at the BSAC OPAT Conference,11 December 2019.
United Kingdom
POSTER: Cefatzidime
Title: Stability testing of ceftazidime solutions for injection in elastomeric devices at 12 mg/mL and 25 mg/mL in 0.9% w/v saline for safe use in Outpatient Parenteral Antimicrobial Therapy (OPAT). Presented at the BSAC OPAT Conference, 11 December 2019.
United Kingdom
POSTER: Meropenem
The influence of pH and buffering on the stability of Meropenem 6.25-25 mg/ml at 32C. Presented at the BSAC OPAT Conference, 11-12th December 2017.
United Kingdom
POSTER: Flucloxacillin
Title: Assessment of the stability of citrate-buffered Flucloxacillin for injection when stored in two commercially available ambulatory devices: INfusor (Baxter) and Accufuser® (Woo Young Medical), a study compliant with the NHS Yellow Cover Document (YCD) requirements. Presented at the BSAC OPAT Conference, 11-12th December 2017.
United Kingdom
POSTER: OPAT flow rate
Title: Outcomes of a National Survey of Experience with Continuous Infusion Elastomeric Devices in OPAT. Presented at the BSAC OPAT Conference, 13-14th December 2018.
United Kingdom
DOCUMENT: OPAT Guidance
Guidance on the pharmaceutical issues concerning OPAT Services and other outpatient intravenous therapies
clindamycin stability antibiotic United Kingdom
Stability of clindamycin 9.52mg/ml in sodium chloride 0.9%
Drug stability study
Piperacillin tazobactam stability antimicrobial United Kingdom
Stability of piperacillin / tazobactam 56.9mg/ml in sodium chloride 0.9%
Drug stability study
piperacillin tazobactam stability antibiotic United Kingdom
Stability of piperacillin / tazobactam 56.9mg/ml in glucose 5%
Drug stability study
clindamycin antibiotic stability United Kingdom
Stability of clindamycin 9.52mg/ml in glucose 5%
Drug stability study