Moxastine: Difference between revisions
Content deleted Content added
m Stub sorting and placement of stub template(s): respiratory-system-drug-stub. See approval. Report errors and suggestions at User talk:PotatoBot. |
+ cite |
||
| (21 intermediate revisions by 18 users not shown) | |||
| Line 1: | Line 1: | ||
{{cs1 config|name-list-style=vanc|display-authors=6}} |
|||
{{Short description|Chemical compound}} |
|||
{{Drugbox |
{{Drugbox |
||
| Verifiedfields = changed |
|||
| verifiedrevid = |
| verifiedrevid = 449583321 |
||
| IUPAC_name = 2-[1,1-di(phenyl)ethoxy]-''N'',''N''-dimethylethanamine |
| IUPAC_name = 2-[1,1-di(phenyl)ethoxy]-''N'',''N''-dimethylethanamine |
||
| image = Moxastine.png |
| image = Moxastine.png |
||
| Line 19: | Line 22: | ||
<!--Identifiers--> |
<!--Identifiers--> |
||
| CAS_number_Ref = {{cascite|correct|??}} |
|||
| CAS_number = 3572-74-5 |
| CAS_number = 3572-74-5 |
||
| ATC_prefix = none |
| ATC_prefix = none |
||
| Line 25: | Line 29: | ||
| UNII_Ref = {{fdacite|correct|FDA}} |
| UNII_Ref = {{fdacite|correct|FDA}} |
||
| UNII = ZSJ254W6SF |
| UNII = ZSJ254W6SF |
||
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} |
|||
| ChemSpiderID = 18062 |
|||
<!--Chemical data--> |
<!--Chemical data--> |
||
| C=18 | H=23 | N=1 | O=1 |
| C=18 | H=23 | N=1 | O=1 |
||
| molecular_weight = 269.38 g/mol |
|||
| smiles = CC(C1=CC=CC=C1)(C2=CC=CC=C2)OCCN(C)C |
| smiles = CC(C1=CC=CC=C1)(C2=CC=CC=C2)OCCN(C)C |
||
| StdInChI_Ref = {{stdinchicite|changed|chemspider}} |
|||
| StdInChI = 1S/C18H23NO/c1-18(20-15-14-19(2)3,16-10-6-4-7-11-16)17-12-8-5-9-13-17/h4-13H,14-15H2,1-3H3 |
|||
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} |
|||
| StdInChIKey = BBIMHFSPNXQFAH-UHFFFAOYSA-N |
|||
}} |
}} |
||
'''Moxastine''' (also known as '''mephenhydramine''') is an [[antihistamine]] and [[anticholinergic]].<ref>{{cite book | vauthors = Saxena AK, Saxena M | chapter = Developments in antihistamines (H1) | veditors = Jucker E | title = Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques | date = 1992 | pages = 35–125 | isbn = 978-3-0348-7146-4 | doi = 10.1007/978-3-0348-7144-0_3 }}</ref> |
|||
'''Moxastine''' is an [[antihistamine]] and [[anticholinergic]]. |
|||
It was developed in Czechoslovakia<ref>{{cite book | vauthors = Wardell WM |title=Controlling the Use of Therapeutic Drugs An International Comparison |date=1978 |publisher=American Enterprise Institute for Public Policy Research |location=Washington, D.C |isbn=978-0-8447-3278-7 |page=242}}</ref> and sold in hydrochloride form as an antihistamine (Alfadryl). |
|||
It is, with [[8-chlorotheophylline]], a component of cocrystal/salt [[moxastine teoclate]] (mephenhydrinate) used as antiemetic (Theadryl; Kinedryl (with caffeine)). |
|||
== References == |
== References == |
||
{{Reflist |
{{Reflist}} |
||
== See also == |
|||
* [[Diphenhydramine]] |
|||
{{Cholinergics}} |
{{Cholinergics}} |
||
{{Histaminergics}} |
{{Histaminergics}} |
||
| ⚫ | |||
| ⚫ | |||
[[Category:Amines]] |
|||
[[Category:H1 receptor antagonists]] |
[[Category:H1 receptor antagonists]] |
||
[[Category:Dimethylamino compounds]] |
|||