From Wikipedia, the free encyclopedia
The printable version is no longer supported and may have rendering errors. Please update your browser bookmarks and please use the default browser print function instead.
Protein-coding gene in the species Homo sapiens
Potassium voltage-gated channel subfamily V member 1 is a protein that in humans is encoded by the KCNV1 gene .[ 5] [ 6] protein encoded by this gene is a voltage-gated potassium channel subunit.[ 5] [ 6]
Common variations in the KCNV1 gene have been associated with schizophrenia.[ 7]
References
^ a b c GRCh38: Ensembl release 89: ENSG00000164794 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022342 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ a b Hugnot JP, Salinas M, Lesage F, Guillemare E, de Weille J, Heurteaux C, Mattei MG, Lazdunski M (Aug 1996). "Kv8.1, a new neuronal potassium channel subunit with specific inhibitory properties towards Shab and Shaw channels" . EMBO J . 15 (13): 3322–31. doi :10.1002/j.1460-2075.1996.tb00697.x . PMC 451895 PMID 8670833 . ^ a b Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev . 57 (4): 473–508. doi :10.1124/pr.57.4.10 . PMID 16382104 . S2CID 219195192 . ^ Schizophrenia Working Group of the Psychiatric Genomics Consortium (2014-07-24). "Biological insights from 108 schizophrenia-associated genetic loci" . Nature . 511 (7510): 421–427. Bibcode :2014Natur.511..421S . doi :10.1038/nature13595 . ISSN 1476-4687 . PMC 4112379 PMID 25056061 .
Further reading
Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Sano A, Mikami M, Nakamura M, et al. (2002). "Positional candidate approach for the gene responsible for benign adult familial myoclonic epilepsy" . Epilepsia . 43 (Suppl 9): 26–31. doi :10.1046/j.1528-1157.43.s.9.7.x PMID 12383276 . S2CID 39236204 . Ebihara M, Ohba H, Kikuchi M, Yoshikawa T (2004). "Structural characterization and promoter analysis of human potassium channel Kv8.1 (KCNV1) gene". Gene . 325 : 89–96. doi :10.1016/j.gene.2003.09.044 . PMID 14697513 . Salinas M, de Weille J, Guillemare E, et al. (1997). "Modes of regulation of shab K+ channel activity by the Kv8.1 subunit" . J. Biol. Chem . 272 (13): 8774–80. doi :10.1074/jbc.272.13.8774 PMID 9079713 .
External links
