By large, most of the chewing gum produced in the world uses a “wet” formulation and the process involves an extrusion. However, there are alternatives to this and today I’d like to talk about a company in the US that excels in the tabletted gum process. PerOs Biosciences produces functional gum using a patented process which differs from other tabletting processes. For example, it does not require a double layer and besides, they claim that the percentage of active ingredient can be larger versus other similar processes. This tabletting involves compressing the gum powder in a tablet press. It is a “dry” formulation, as the ingredients are all (or a huge majority) in powder form. This is specially interesting when the active that has to be added is sensitive to temperature. The whole process is carried out at room temperature (or at least there is no significant heating as in the extrusion), so very convenient when the active can be damaged by heat.
The company has some success cases, collaborations and studies with different entities. Maybe an interesting one is the one related to an anti-viral chewing gum ( so, it might prevent Covid19) carried out together with the University of Pennsylvania.
As not many companies in the world are proficient in tabletting chewing gum, this is one that has to be considered, for sure.