| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Eternals | - | - | - | $151,731,669 | 4,090 | $164,870,234 | Nov 5 | Walt Disney Studios Motion Pictures | false |
| 2 | Ghostbusters: Afterlife | - | - | - | $89,950,119 | 4,315 | $129,360,575 | Nov 19 | Sony Pictures Releasing | false |
| 3 | Clifford the Big Red Dog | - | - | - | $43,520,629 | 3,700 | $48,947,356 | Nov 10 | Paramount Pictures | false |
| 4 | Encanto | - | - | - | $43,228,940 | 3,980 | $96,093,622 | Nov 24 | Walt Disney Studios Motion Pictures | false |
| 5 | Dune: Part One | - | - | - | $33,198,985 | 4,125 | $108,327,830 | Oct 22 | Warner Bros. | false |
| 6 | No Time to Die | - | - | - | $25,088,845 | 4,407 | $160,891,007 | Oct 8 | Metro-Goldwyn-Mayer (MGM) | false |
| 7 | House of Gucci | - | - | - | $24,641,198 | 3,477 | $53,809,574 | Nov 24 | United Artists Releasing | false |
| 8 | Venom: Let There Be Carnage | - | - | - | $19,275,718 | 4,225 | $213,550,366 | Oct 1 | Sony Pictures Releasing | false |
| 9 | King Richard | - | - | - | $11,821,603 | 3,302 | $15,129,285 | Nov 19 | Warner Bros. | false |
| 10 | Ron's Gone Wrong | - | - | - | $10,211,092 | 3,560 | $23,009,270 | Oct 22 | 20th Century Studios | false |
| 11 | The French Dispatch | - | - | - | $10,135,021 | 1,225 | $16,124,375 | Oct 22 | Searchlight Pictures | false |
| 12 | Resident Evil: Welcome to Raccoon City | - | - | - | $9,777,845 | 2,803 | $17,000,612 | Nov 24 | Screen Gems | false |
| 13 | Spencer | - | - | - | $6,691,121 | 1,265 | $7,086,632 | Nov 5 | Neon | false |
| 14 | Antlers | - | - | - | $6,247,442 | 2,800 | $10,619,670 | Oct 29 | Searchlight Pictures | false |
| 15 | Halloween Kills | - | - | - | $6,097,405 | 3,727 | $92,002,155 | Oct 15 | Universal Pictures | false |
| 16 | My Hero Academia: World Heroes' Mission | - | - | - | $5,948,453 | 1,585 | $12,271,658 | Oct 29 | FUNimation Entertainment | false |
| 17 | Last Night in Soho | - | - | - | $5,943,190 | 3,016 | $10,127,625 | Oct 29 | Focus Features | false |
| 18 | Belfast | - | - | - | $5,188,695 | 1,255 | $9,250,870 | Nov 12 | Focus Features | false |
| 19 | The Addams Family 2 | - | - | - | $3,775,714 | 4,207 | $56,489,153 | Oct 1 | United Artists Releasing | false |
| 20 | Sooryavanshi | - | - | - | $3,547,776 | 491 | $3,547,776 | Nov 5 | Reliance Entertainment | false |
| 21 | Shang-Chi and the Legend of the Ten Rings | - | - | - | $1,781,305 | 4,300 | $224,543,292 | Sep 3 | Walt Disney Studios Motion Pictures | false |
| 22 | The Last Duel | - | - | - | $778,410 | 3,065 | $10,853,945 | Oct 15 | 20th Century Studios | false |
| 23 | C'mon C'mon | - | - | - | $528,755 | 569 | $1,863,674 | Nov 19 | A24 | false |
| 24 | Anita | - | - | - | $450,640 | 15 | $556,632 | Nov 12 | CMC Pictures | false |
| 25 | L'Arracheuse de temps | - | - | - | $444,584 | 72 | $750,623 | Nov 19 | - | false |
| 26 | Licorice Pizza | - | - | - | $443,825 | 1,977 | $17,318,007 | Nov 26 | United Artists Releasing | false |
| 27 | For the Love of Money | - | - | - | $326,857 | 519 | $480,774 | Nov 24 | Freestyle Releasing | false |
| 28 | India Sweets and Spices | - | - | - | $272,763 | 343 | $288,714 | Nov 19 | Bleecker Street Media | false |
| 29 | The Battle at Lake Changjin | - | - | - | $261,856 | 20 | $342,411 | Nov 19 | CMC Pictures | false |
| 30 | Aline | - | - | - | $239,227 | 72 | $667,815 | Nov 26 | Roadside Attractions | false |
| 31 | Julia | - | - | - | $236,711 | 288 | $399,811 | Nov 12 | Sony Pictures Classics | false |
| 32 | Free Guy | - | - | - | $233,404 | 4,165 | $121,626,598 | Aug 13 | 20th Century Studios | false |
| 33 | A Revision | - | - | - | $152,743 | 51 | $161,074 | Nov 5 | - | false |
| 34 | The Rescue | - | - | - | $149,012 | 561 | $1,060,556 | Oct 8 | Greenwich Entertainment | false |
| 35 | A Mouthful of Air | - | - | - | $138,734 | 816 | $269,435 | Oct 29 | Stage 6 Films | false |
| 36 | Dear Evan Hansen | - | - | - | $103,446 | 3,364 | $15,002,646 | Sep 24 | Universal Pictures | false |
| 37 | Jungle Cruise | - | - | - | $89,542 | 4,310 | $116,987,516 | Jul 30 | Walt Disney Studios Motion Pictures | false |
| 38 | Ghostbusters 2021 Re-release | - | - | - | $87,401 | 774 | $391,718 | Oct 29 | Sony Pictures Classics | false |
| 39 | The Souvenir: Part II | - | - | - | $73,789 | 42 | $98,929 | Oct 29 | A24 | false |
| 40 | The First Wave | - | - | - | $62,376 | 11 | $62,376 | Nov 19 | Neon | false |
| 41 | Christmas vs. The Walters | - | - | - | $55,121 | 80 | $55,121 | Nov 5 | Safier Entertainment | false |
| 42 | Kurt Vonnegut: Unstuck in Time | - | - | - | $50,392 | 69 | $60,389 | Nov 19 | IFC Films | false |
| 43 | Candyman | - | - | - | $43,655 | 3,569 | $61,186,570 | Aug 27 | Universal Pictures | false |
| 44 | The Youngest Evangelist | - | - | - | $35,750 | 233 | $35,750 | Nov 19 | Atlas Distribution Company | false |
| 45 | The Beta Test | - | - | - | $30,520 | 25 | $30,520 | Nov 5 | IFC Films | false |
| 46 | Becoming Cousteau | - | - | - | $27,343 | 319 | $231,687 | Oct 22 | Picturehouse | false |
| 47 | Mass | - | - | - | $24,139 | 59 | $145,174 | Oct 8 | Bleecker Street Media | false |
| 48 | Bad Luck Banging or Loony Porn | - | - | - | $22,957 | 16 | $72,342 | Nov 19 | Magnolia Pictures | false |
| 49 | Drive My Car | - | - | - | $22,555 | 213 | $2,352,240 | Nov 24 | Janus Films | false |
| 50 | Bergman Island | - | - | - | $12,787 | 115 | $145,191 | Oct 15 | IFC Films | false |
| 51 | What Do We See When We Look at the Sky? | - | - | - | $11,577 | 4 | $21,443 | Nov 12 | MUBI | false |
| 52 | Cicada | - | - | - | $11,170 | 4 | $13,370 | Oct 29 | Strand Releasing | false |
| 53 | I'm Your Man | - | - | - | $10,999 | 122 | $275,155 | Sep 24 | Bleecker Street Media | false |
| 54 | I Was a Simple Man | - | - | - | $10,452 | 6 | $12,669 | Nov 19 | Strand Releasing | false |
| 55 | Cry Macho | - | - | - | $9,533 | 4,022 | $10,310,734 | Sep 17 | Warner Bros. | false |
| 56 | Wife of a Spy | - | - | - | $8,396 | 21 | $69,464 | Sep 17 | Kino Lorber | false |
| 57 | Breathless 2021 Re-release | - | - | - | $7,178 | 7 | $51,142 | Sep 24 | Rialto Pictures | false |
| 58 | The Feast | - | - | - | $6,910 | 22 | $8,316 | Nov 19 | IFC Films | false |
| 59 | Unoponchash Batash | - | - | - | $6,033 | 15 | $6,033 | Nov 19 | Swapna Scarecrow | false |
| 60 | Only the Animals | - | - | - | $5,749 | 6 | $9,138 | Oct 29 | Cohen Media Group | false |
| 61 | The Eyes of Tammy Faye | - | - | - | $5,664 | 1,352 | $2,404,127 | Sep 17 | Searchlight Pictures | false |
| 62 | The Lost Leonardo | - | - | - | $4,628 | 217 | $445,740 | Aug 13 | Sony Pictures Classics | false |
| 63 | Luzzu | - | - | - | $3,982 | 5 | $39,948 | Oct 15 | Kino Lorber | false |
| 64 | Golden Voices | - | - | - | $3,848 | 14 | $32,250 | Oct 8 | Music Box Films | false |
| 65 | The Many Saints of Newark | - | - | - | $3,711 | 3,181 | $8,237,403 | Oct 1 | Warner Bros. | false |
| 66 | Love It Was Not | - | - | - | $3,688 | 3 | $3,688 | Nov 5 | Greenwich Entertainment | false |
| 67 | Learning to Live Together: The Return of Mad Dogs & Englishmen | - | - | - | $3,564 | 4 | $18,293 | Oct 22 | Abramorama | false |
| 68 | The Laws of the Universe: The Age of Elohim | - | - | - | $3,555 | 7 | $15,750 | Oct 22 | Freestyle Releasing | false |
| 69 | Writing with Fire | - | - | - | $3,423 | 9 | $28,262 | Nov 26 | Music Box Films | false |
| 70 | The Incredibly True Adventure of Two Girls in Love 2021 Re-release | - | - | - | $3,027 | 1 | $3,519 | Nov 24 | Strand Releasing | false |
| 71 | Minyan | - | - | - | $3,024 | 3 | $11,451 | Oct 22 | Strand Releasing | false |
| 72 | Below the Fold | - | - | - | $2,675 | 1 | $3,550 | Nov 19 | Mutiny Pictures | false |
| 73 | In Balanchine's Classroom | - | - | - | $2,384 | 9 | $76,650 | Sep 17 | Zeitgeist Films | false |
| 74 | My Country, My Parents | - | - | - | $1,996 | 51 | $177,133 | Oct 8 | CMC Pictures | false |
| 75 | On Broadway | - | - | - | $1,653 | 63 | $82,733 | Aug 20 | Kino Lorber | false |
| 76 | The Alpinist | - | - | - | $1,519 | 245 | $844,743 | Sep 10 | Roadside Attractions | false |
| 77 | Tango Shalom | - | - | - | $1,504 | 29 | $102,651 | Sep 3 | Vision Films | false |
| 78 | Ascension | - | - | - | $1,028 | 6 | $17,200 | Oct 8 | MTV Documentary Films | false |
| 79 | I Need You Dead! | - | - | - | $790 | 1 | $790 | Nov 26 | Mutiny Pictures | false |
| 80 | Labyrinth of Cinema | - | - | - | $728 | 5 | $4,501 | Oct 20 | MTV Documentary Films | false |
| 81 | Azor | - | - | - | $706 | 52 | $53,932 | Sep 10 | MUBI | false |
| 82 | Little Girl | - | - | - | $607 | 7 | $10,776 | Sep 17 | Music Box Films | false |
| 83 | Dear Rider: The Jake Burton Story | - | - | - | $552 | 2 | $552 | Nov 5 | Greenwich Entertainment | false |
| 84 | Falling for Figaro | - | - | - | $480 | 44 | $35,910 | Oct 1 | IFC Films | false |
| 85 | Shiva Baby | - | - | - | $284 | 27 | $159,294 | Apr 2 | Utopia | false |
| 86 | Nine Days | - | - | - | $252 | 443 | $694,849 | Jul 30 | Sony Pictures Classics | false |
| 87 | Hard Luck Love Song | - | - | - | $231 | 172 | $69,746 | Oct 15 | Roadside Attractions | false |
| 88 | Ema | - | - | - | $120 | 27 | $53,437 | Aug 13 | Music Box Films | false |
