My steps:
conda install -c conda-forge -c bioconda hhsuite
hhblits -i A.fasta -d pdb70 -oa3m A.a3m
hhmake -i A.a3m -o A.hhm

My question:
Can *and NULL in the generated hhm file be considered to mean the same thing? Can I replace * with the corresponding NULL value in each column? Your reply is very urgent.Thank you very much.

Part of the generated hhm file

NULL 3706 5728 4211 4064 4839 3729 4763 4308 4069 3323 5509 4640 4464 4937 4285 4423 3815 3783 6325 4665
HMM A C D E F G H I K L M N P Q R S T V W Y
……
……
A 53 3804 6047 3909 4101 5190 3304 5880 5674 4475 4428 5009 3773 4662 4265 4139 3802 3149 3643 * 6068 53