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Custom templates when doing a series of runs #265

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TieliangGan opened this issue Oct 22, 2024 · 1 comment
Open

Custom templates when doing a series of runs #265

TieliangGan opened this issue Oct 22, 2024 · 1 comment

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@TieliangGan
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Hi! So recently I have been using ColabFold to predict hundreds of multimers. I use a directory which contains many fasta files in it. Within different fasta files, only one sequence of the multimer changes while other stays the same. Is there any way to tell the program to reuse the templates that it has found in the previous run and forward it to the next time?

example: there are two fasta files in the directory named a.fasta and b.fasta, the sequence for a.fasta is AAA:XXX and b.fasta is BBB:XXX. I use this directory as input. so after finishing a.fasta, how to tell the program to reuse the template for b.fasta?

Thank you very much for your help!

@TieliangGan
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so to follow up, I managed to use the template directory generated by my previous run as a custom template in my subsequent runs. however, there are some different logs poping up: as the one of the chain in my file is de novo designed, it should not find any templates ( and it is the case when I am not using the custom template generated by my previous runs). however, when I am using the template directory generated by my previous runs, the log says that the chain I designed found templates. These templates are in fact templates for my other chain. So will this be a problem? Thank you very much!

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