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Pharmaceuticals and vector-control programmes have greatly diminished the once-widespread disease, but sustained effort will be needed to stamp out infection for good.
Diverse methyl β-CâH functionalizations of ketones and esters are enabled by cationic Pd(II) complexes with MPANA ligands, offering access to spirocyclic and fused ring systems through enhanced catalystâsubstrate affinity.
We discuss the potential consequences and ethical concerns of polygenic genome editing of human embryos to alter specific variants associated with polygenic diseases, highlighting the possibility of reducing disease susceptibility while exacerbating health inequalities.
Using high-density electrophysiological recordings, how internally generated cell assemblies are updated by action plans to meet external goals is explored.