scripts
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## HGNC download is from gene families site at HGNC, where gene is in the 2nd column & family name is in the 11th column ## Protein kinase lists can be obtained from numerous sources. The format expected for use below is gene\tfamily ## Drug class info can be obtained via DrugBank/DrugPort, NIH, and others. The format used below expects two columns drug\tclass ## Ensembl .gtf was necessary for longest transcript calculation. Run determine_transcript_lengths.pl to get gene, transcript, length (gtl) data. # annotated .clusters with a variety of details. These simply append columns, and so they can accumulate. annotate_clusters_MAF.pl #expects gtl data and the .maf used for clustering annotate_clusters_PDB.pl #needs HotSpot3D data annotate_clusters_domains.pl #needs HotSpot3D data annotate_clusters_drug_class.pl #expects a drug class list annotate_clusters_HGNC_Kinase.pl #expects HGNC download & protein kinase list annotate_clusters_families.pl #expects HGNC download # determine cluster presence/representation for PDB structures associated with the gene clusterPDBPresence.drug.pl #for drug-mutation pairs/clusters clusterPDBPresence.pl #for mutation-mutation pairs/clusters genePDBPresence.pl #for genes instead of clusters #determine number of structures for each gene nStructures.pl