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ENZYME

ENZYME entry: EC 4.6.1.1

Accepted Name
adenylate cyclase
Alternative Name(s)
3',5'-cyclic AMP synthetase
adenyl cyclase
adenylyl cyclase
ATP pyrophosphate-lyase
Reaction catalysed
ATP = 3',5'-cyclic AMP + diphosphate
Comment(s)
  • Also acts on dATP to form 3',5'-cyclic dAMP.
  • Requires pyruvate.
  • Activated by NAD(+) in presence of EC 2.4.2.31.
Cross-references
BRENDA4.6.1.1
EC2PDB4.6.1.1
ExplorEnz4.6.1.1
PRIAM enzyme-specific profiles4.6.1.1
KEGG Ligand Database for Enzyme Nomenclature4.6.1.1
IUBMB Enzyme Nomenclature4.6.1.1
IntEnz4.6.1.1
MEDLINEFind literature relating to 4.6.1.1
MetaCyc4.6.1.1
Rhea expert-curated reactions4.6.1.1
UniProtKB/Swiss-Prot
Q9VP76,�AC78C_DROMEP83855,�ACLP_MOUSEQ9VK50,�ACXE_DROME
P19754,�ADCY1_BOVINQ08828,�ADCY1_HUMANO88444,�ADCY1_MOUSE
Q9VW60,�ADCY2_DROMEQ08462,�ADCY2_HUMANQ80TL1,�ADCY2_MOUSE
P26769,�ADCY2_RATO60266,�ADCY3_HUMANQ8VHH7,�ADCY3_MOUSE
P21932,�ADCY3_RATQ8NFM4,�ADCY4_HUMANQ91WF3,�ADCY4_MOUSE
P26770,�ADCY4_RATP30803,�ADCY5_CANLFO95622,�ADCY5_HUMAN
P84309,�ADCY5_MOUSEP40144,�ADCY5_RABITQ04400,�ADCY5_RAT
P30804,�ADCY6_CANLFO43306,�ADCY6_HUMANQ01341,�ADCY6_MOUSE
Q03343,�ADCY6_RATQ29450,�ADCY7_BOVINP51828,�ADCY7_HUMAN
P51829,�ADCY7_MOUSEP40145,�ADCY8_HUMANP97490,�ADCY8_MOUSE
P40146,�ADCY8_RATQ9DGG6,�ADCY9_CHICKO60503,�ADCY9_HUMAN
P51830,�ADCY9_MOUSEP98999,�ADCY9_XENLAQ96PN6,�ADCYA_HUMAN
Q8C0T9,�ADCYA_MOUSEQ866F4,�ADCYA_RABITQ9Z286,�ADCYA_RAT
Q99279,�CY41_TRYBBQ99396,�CY42_TRYBBQ99280,�CY43_TRYBB
P32870,�CYA1_DROMEP0A4Y1,�CYA1_MYCBOP9WQ34,�CYA1_MYCTO
P9WQ35,�CYA1_MYCTUP19485,�CYA1_RHIMEQ52915,�CYA2_RHIME
Q9Z3Q0,�CYA3_RHIMEQ26721,�CYA4_TRYBBQ59119,�CYAA_AERHY
P43524,�CYAA_ANACYP40136,�CYAA_BACANQ57506,�CYAA_BORBR
J7QLC0,�CYAA_BORP1P0DKX7,�CYAA_BORPEP40130,�CYAA_DICCH
Q03100,�CYAA_DICDIQ8XAP1,�CYAA_ECO57Q8FBP0,�CYAA_ECOL6
P00936,�CYAA_ECOLIP27580,�CYAA_GLUNIP40134,�CYAA_HAEIN
P23466,�CYAA_LACKLQ27675,�CYAA_LEIDOQ01631,�CYAA_NEUCR
Q05766,�CYAA_PASMUQ01513,�CYAA_PODASQ59685,�CYAA_PROMI
P0A1A8,�CYAA_SALTIP0A1A7,�CYAA_SALTYP14605,�CYAA_SCHPO
P59739,�CYAA_SHIFLP40137,�CYAA_STIAUP40135,�CYAA_STRCO
Q9WXC3,�CYAA_STRGRQ26896,�CYAA_TRYCOP26338,�CYAA_TRYEQ
P49606,�CYAA_USTMAP08678,�CYAA_YEASTP30528,�CYAA_YERIN
P40127,�CYAA_YERPEO69199,�CYAB_AERHYQ25263,�CYAB_LEIDO
P40138,�CYAB_STIAUQ55F68,�CYAD_DICDIQ03101,�CYAG_DICDI
O07732,�LIPJ_MYCTUQ8S9F2,�PCYAA_EUGGRQ76L34,�PCYAA_EUGLO
Q8S9F1,�PCYAB_EUGGRQ76L33,�PCYAB_EUGLOP9WMU8,�Y1264_MYCTO
P9WMU9,�Y1264_MYCTUQ57692,�Y240_METJA

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.6.-.-
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