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Dog Vaccination Costs

Depending on vaccine type and vet fees in your area, dog vaccinations typically cost between $20 and $60
Key Takeaways
  • Dog vaccinations cost $20 to $60 each, on average. Veterinarians generally classify dog vaccinations into two groups: core and non-core.
  • Puppies typically receive three key vaccinations during their first four months of life. Core vaccines are usually combined and administered in a single injection.
  • Pet insurance plans usually don’t cover vaccines, but you can often add wellness coverage that reimburses you for vaccination costs.

Dog vaccinations can protect your furry friend, as well as humans and other pets in the community, from various — and even deadly — diseases. Vaccine costs can add up quickly, especially for young puppies, but these basic services are considered essential to your pet’s health. If you are looking to offset costs, pet insurance will typically only cover vaccines if you buy a wellness plan for routine care.

We at the MarketWatch Guides team want pet parents to understand and budget for this necessary expense as part of the cost of owning a dog, so we’ve gathered everything pet owners should know about dog vaccinations in the article below.

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Our Top Pick
Best Digital Experience
4.6
Monthly Cost for Dogs $46
Monthly Cost for Cats $21
Explore Plans on Lemonade’s website
Best for Lifelong Protection
4.6
Monthly Cost for Dogs $46
Monthly Cost for Cats $23
Explore Plans on ASPCA’s website
Most Comprehensive Coverage
4.6
Monthly Cost for Dogs $49
Monthly Cost for Cats $24
Explore Plans on Spot’s website
Our Pick for Wellness Plan Coverage
4.8
Monthly Cost for Dogs $47
Monthly Cost for Cats $26
Explore Plans on Embrace’s website

What’s the Cost of Dog Vaccinations?

According to CareCredit, dog vaccinations typically cost between $20 and $50 each, depending on the vaccine type and broader veterinary fees in your area. Vaccines are typically administered during your dog’s annual wellness visit, so the total visit cost includes an exam fee and will vary based on how many vaccines your dog receives. Here is a breakdown of the expenses by vaccination type based on our research into dog vaccination costs.

VaccineAverage Price
Bordetella$36
Distemper, hepatitis parainfluenza and parvovirus (DHPP)$45
Influenza (H3N2 and H3N8)$50
Leptospirosis$25
Rabies$30
Data courtesy CareCredit and updated as of Oct. 2025

According to VCA Animal Hospitals, puppies receive antibodies from their mother’s milk that temporarily protect them against infectious diseases, but that protection wanes after several weeks. Pet vaccinations start around 6 to 8 weeks of age, with doses given every two to four weeks until a dog is 16 weeks old. This enables the puppy to make antibodies on their own. Puppy vaccinations are customized to each pet, depending on their current and expected lifestyle and needs.

Pet insurance can help cover the costs of dog vaccinations through pet wellness plans with routine care coverage. The best pet insurance companies offer unique plan options that can cover the vaccines your dog needs.

Core Vaccines

Common vaccines for dogs include core and non-core vaccinations, according to the AAHA, which are categorized based on disease severity and prevalence. Core vaccines are considered necessary for all pets to protect against often fatal diseases and help protect the larger community from outbreaks. Core vaccines for dogs include:

  • Canine parvovirus vaccine: Canine parvovirus or parvo is highly contagious and attacks a dog’s gastrointestinal tract and immune system, leading to severe dehydration, systemic infection and shock. Most puppies will survive with treatment, but treatment requires intensive care, which can be costly.
  • Distemper vaccine: Canine distemper virus attacks the nervous system and respiratory tract and is often fatal. Dogs that survive typically have permanent neurologic damage. Wildlife can carry and transmit the virus, serving as a reservoir of infection.
  • Canine hepatitis vaccine: Canine infectious hepatitis, which is caused by an adenovirus, attacks liver cells and can cause secondary clotting problems or kidney disorders. Around 10% to 30% of infected young dogs will die from the disease, but vaccination provides immunity.
  • Rabies vaccine: Rabies virus is nearly 100% fatal, attacking the brain and nervous system within days of infection. The virus is prevalent in many wildlife species, such as raccoons and bats, and is transmitted through bite wounds. The rabies vaccine is extremely effective and is required by law to protect pets and humans from infection.

What Is the 5-in-1 Vaccine?

According to our research, the 5-in-1 or 4-in-1 vaccine for dogs combines core vaccines into a single injection. Parvovirus, distemper, adenovirus and canine parainfluenza comprise the 4-in-1 vaccine. The 5-in-1 vaccine also includes protection against leptospirosis. This combination is often referred to as the DAPP, DHPP, DA2PP or DAPP+L vaccination, or the canine distemper combination vaccine. Most veterinary clinics use the combination vaccine to minimize the number of injections required.

Optional Dog Vaccines

Optional dog vaccines are also known as lifestyle or non-core vaccines and are administered only to pets at high risk for contracting each disease. A dog’s risk level is assessed during puppyhood and then reassessed during each annual wellness visit to determine whether their vaccine protocol is appropriate. According to our research, optional vaccines for dogs include:

  • Bordetella vaccine: The Bordetella vaccine protects against the bacteria that commonly cause kennel cough and is recommended for dogs who spend time at parks, daycare, boarding kennels or training classes. This vaccine does not prevent infection, but it lessens infection severity and helps dogs recover faster.
  • Canine influenza vaccine: Dogs at risk of Bordetella infection are also at risk of canine influenza, an airborne infection. The canine influenza vaccine does not prevent infection, but it can lessen disease severity and reduce the likelihood of complications, including pneumonia.
  • Leptospirosis vaccine: Leptospirosis is a bacterial disease that dogs can pick up from water sources contaminated with infected urine. Leptospirosis causes severe liver and kidney damage and can become fatal for some dogs. Vaccination provides effective immunity.
  • Lyme disease vaccine: Ticks transmit Lyme disease, which is caused by Borrelia burgdorferi. This vaccine is recommended for pets that spend time outdoors, and especially pets who go hiking or camping with their owner.

What’s the Best Puppy Vaccination Schedule?

The best vaccination schedule for your puppy depends on when injections begin and how many total vaccines they need. Pet parents can expect to schedule regular vet visits every few weeks until their puppy is at least 4 months old. Here is an overview of a typical puppy vaccination schedule:

AgeVaccine
6–7 WeeksDistemper, hepatitis, parvovirus, parainfluenza and leptospirosis (DHPPi+L)
9–10 WeeksDHPPi+L booster
12–16 WeeksDHPPi+L booster, rabies
1 yearDHPPi+L, Bordetella, canine influenza, leptospira, Lyme disease, coronavirus
AnnuallyBordatella, canine influenza, leptospira, Lyme disease, coronavirus, parainfluenza
Every 3 yearsDHPPi+L booster
Source: American Animal Hospital Association
Data updated as of Oct. 2025

How Often Do Dogs Need Vaccines?

After the initial puppy vaccination series, adult dogs need vaccine boosters throughout their lives. The first vaccine stimulates the immune system to produce antibodies to fight the targeted disease, while boosters help to reinforce this response.

Your dog should get booster shots for each vaccination one year after the puppy series ends. After this, dogs receive vaccines every one to three years, depending on the manufacturer’s labeling and veterinarians’ recommendations.

VaccineDoseTimelineBooster
Distemper, Hepatitis, Parvovirus, and Parainfluenza3 doses2-4 weeks apart1 year after initial vaccination series, boosters every 3 years
RabiesAs required by state lawAs required by state lawAs required by state law
Leptospira2 doses2-4 weeks apart, starting at 12 weeksAnnually
Canine Lyme Disease2 doses2-4 weeks apartAnnually
Bordetella1 doseAnnually
Canine Parainfluenza1 doseAnnually
Canine Influenza2 doses2-4 weeks apartAnnually
Source: American Animal Hospital Association
Data Updated as of Oct. 2025

Are Dog Vaccinations Required?

Rabies vaccination is required under state or local laws, often set by the county government. Typically, local animal control departments enforce these laws and work with local veterinarians to protect pets in their communities.

No other dog vaccinations are required. However, the DAPP vaccine combination, which includes four core vaccines — canine distemper, adenovirus, parainfluenza and parvovirus — is highly recommended to protect your pet and others in your community.


How To Lower the Cost of Vaccines for Dogs

Pet parents can lower the costs of puppy vaccines by adopting a dog from a shelter or rescue organization, which may include vaccination costs in the initial adoption fee. You can lower adult dog vaccination costs using the following strategies:

  • Visit low-cost vaccine clinics in your area
  • Re-evaluate your dog’s vaccine risk with your veterinarian each year
  • Adopt an every-three-years vaccine protocol if appropriate
  • Ask your veterinarian about vaccination packages that bundle costs

Remember that low-cost vaccination clinics provide vaccinations only — a complete physical examination and other wellness services are still recommended annually for all pets.

Pet Insurance for Dogs

You can purchase a pet health insurance policy for your dog to cover expenses related to accidents or illnesses. You will pay a monthly premium to keep your policy active, and the insurance company will reimburse you for a percentage of the costs associated with your pet’s care, minus any deductible.

While pet insurance plans help to ensure you’re financially prepared for the unexpected, most policies do not cover wellness or preventive pet care services, including vaccinations. For an additional fee, you can add wellness coverage to some policies. This coverage will reimburse you up to a certain amount for vaccinations and other services, such as a microchip, heartworm test, heartworm prevention, deworming and spaying or neutering.

What Pet Insurance Could Save You

Let’s say your pet needs four vaccinations, which cost $160 total. With a pet insurance plan that has an 80% reimbursement rate and a $50 deductible, you would pay around $20 out of pocket if you have a plan that includes vaccine coverage.

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The listings that appear are from companies from which this website may receive compensation, which may impact how, where and in what order products appear. Not all companies, products or offers were reviewed in connection with this listing.

Our Top Pick
Best Digital Experience
4.6
Monthly Cost for Dogs $46
Monthly Cost for Cats $21
Explore Plans on Lemonade’s website
Best for Lifelong Protection
4.6
Monthly Cost for Dogs $46
Monthly Cost for Cats $23
Explore Plans on ASPCA’s website
Most Comprehensive Coverage
4.6
Monthly Cost for Dogs $49
Monthly Cost for Cats $24
Explore Plans on Spot’s website
Our Pick for Wellness Plan Coverage
4.8
Monthly Cost for Dogs $47
Monthly Cost for Cats $26
Explore Plans on Embrace’s website

Frequently Asked Questions: Cost of Dog Vaccinations

Below, we answer some frequently asked questions about the cost of dog vaccinations:

The 4-in-1 DAPP combination vaccine for puppies, which covers distemper, adenovirus parainfluenza and parvovirus, costs an average of $33 to $38 per dose. The 5-in-1 vaccine, which adds the leptospirosis vaccine, may cost a bit more, with lepto shots costing around $20 to $24 when administered alone.

All dogs should receive core vaccines, including distemper, hepatitis, parvo and rabies vaccines. The rabies vaccine is legally required in all states. Talk with your pet’s veterinarian to learn more about necessary vaccines.

Unvaccinated dogs are more likely to be threatened by infectious diseases than vaccinated dogs. Unvaccinated puppies could become sick within their first few months of life, suffer long-term complications, and possibly die as a result.

Puppies should receive their first vaccinations between 6 and 8 weeks of age. A breeder or shelter may provide the first vaccinations before you bring your pet home. Schedule a visit with your veterinarian as soon as you adopt a new pet, and bring their vaccination records with you to determine when they need their next booster.


Our Methodology

We review each pet insurance company based on factors most important to pet parents like you. Our process includes in-depth industry research into each provider, such as comparing coverage options, gathering quotes online to determine pricing and reading reviews to assess customer service. To better inform our reviews, we’ve surveyed 3,000 dog and cat owners nationwide to determine the most important elements of pet insurance coverage. We’ve also bought pet insurance plans for 10 of our team’s pets to test the customer experience of various providers for ourselves. 

We then score each provider on a 100-point scale and calculate an overall rating out of five stars. Here are more details about the factors we consider when reviewing pet insurance providers:

  • Costs and Discounts (22.5%): To assess pricing, we collected sample quotes for 10 mixed-breed and purebred dogs and cats, ranging from 3 months to 8 years old. Our team collected a total of 17,330 quotes directly from 22 provider’s websites, requesting at least two quotes for all 50 U.S. states from every insurer and pet profile. Providers earn the most points in this category for offering affordable coverage and more than four discount options to customers. 
  • Coverage (22.5%): The best pet insurance companies offer a range of plans, customization options and more so pet owners can choose the right coverage. Companies offering a wide variety of coverage options earn full points in this category. We also look at waiting periods and award the most points if companies offer policies with shorter waiting periods than its competitors. 
  • Covered Treatments (17.5%): According to our survey of pet owners, coverage is one of the most important factors when shopping for pet insurance. Companies with a breadth of included treatments and unique coverages as standard within their policies receive more points in this category than those with less options.
  • Customer Experience (17.5%): Respondents to our survey also valued customer service when comparing pet insurance providers. We score each company based on its website accessibility and overall usability, customer service, mobile apps, money-back guarantees and veterinarian telehealth options. The insurers with the most customer experience offerings receive the most points.
  • Industry Standing (10%): We review up-to-date ratings and accreditation information from the Better Business Bureau (BBB) and Trustpilot, and score companies based on customer reviews and years of industry experience.
  • Availability (10%): Some companies do not offer policies for pets over a certain age. For this category, we deduct points from providers that have age limits for older pets. We also consider state availability, international coverage and if a company extends coverage options to breeds considered dangerous.

We use our rating system to compare each company we review and determine the best pet insurance companies in the industry. To learn more, read our full pet insurance methodology to see how we review and score providers. 

If you have feedback or questions about this article, please email our team at editors@marketwatchguides.com.

Meet the Team

Daniel Mattia is a researcher and writer for MarketWatch Guides with nearly 10 years of experience writing about auto insurance, warranties, lending and personal finance. A former licensed insurance producer, he previously wrote for Yahoo! Personal Finance, RateGenius, Bestow and other publications.

Learn more about Daniel Mattia

Shelby Fishman is an assistant editor for MarketWatch Picks. Previously, she served as an assistant editor for custom content at Barron’s Group. Shelby studied broadcast journalism at Southern Methodist University in Dallas and received her Master’s in Journalism from American University in Washington, D.C.

Learn more about Shelby Fishman
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